BDBM223291 Pentostatin (PTN)

SMILES: OC[C@H]1O[C@H](C[C@@H]1O)n1cnc2[C@H](O)CN=CNc12

InChI Key: InChIKey=FPVKHBSQESCIEP-JQCXWYLXSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 223291   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Adenosine deaminase 3 (SanADA3) (Streptomyces antibioticus)	BDBM223291 (Pentostatin (PTN)) Show SMILES OC[C@H]1O[C@H](C[C@@H]1O)n1cnc2[C@H](O)CN=CNc12 |c:16| Show InChI InChI=1S/C11H16N4O4/c16-3-8-6(17)1-9(19-8)15-5-14-10-7(18)2-12-4-13-11(10)15/h4-9,16-18H,1-3H2,(H,12,13)/t6-,7+,8+,9+/m0/s1	UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	1	-12.5	n/a	n/a	n/a	n/a	n/a	7.2	30
Wuhan University					Assay Description For the ADA activity assay, a reaction comprising 50 mM potassium phosphate buffer (pH 7.2), 0.1 mM Ara-A or adenosine, and 20 mg ADA was conducted a...				Cell Chem Biol 24: 171-181 (2017) Article DOI: 10.1016/j.chembiol.2016.12.012 BindingDB Entry DOI: 10.7270/Q2RF5SXF
					More data for this Ligand-Target Pair
Adenosine deaminase 3 (SanADA3) (Streptomyces antibioticus)	BDBM223291 (Pentostatin (PTN)) Show SMILES OC[C@H]1O[C@H](C[C@@H]1O)n1cnc2[C@H](O)CN=CNc12 |c:16| Show InChI InChI=1S/C11H16N4O4/c16-3-8-6(17)1-9(19-8)15-5-14-10-7(18)2-12-4-13-11(10)15/h4-9,16-18H,1-3H2,(H,12,13)/t6-,7+,8+,9+/m0/s1	UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	2.10	-12.0	n/a	n/a	n/a	n/a	n/a	7.2	30
Wuhan University					Assay Description For the ADA activity assay, a reaction comprising 50 mM potassium phosphate buffer (pH 7.2), 0.1 mM Ara-A or adenosine, and 20 mg ADA was conducted a...				Cell Chem Biol 24: 171-181 (2017) Article DOI: 10.1016/j.chembiol.2016.12.012 BindingDB Entry DOI: 10.7270/Q2RF5SXF
					More data for this Ligand-Target Pair