BDBM22453 2-(cyclohexylamino)-5-methyl-5-propyl-4,5-dihydro-1,3-thiazol-4-one::2-Amino-1,3-thiazol-4(5H)-one, 6a

SMILES: CCCC1(C)SC(NC2CCCCC2)=NC1=O

InChI Key: InChIKey=NSCDVAPHBMDBSY-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 22453   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
11-beta-hydroxysteroid dehydrogenase 1 (Homo sapiens (Human))	BDBM22453 (2-(cyclohexylamino)-5-methyl-5-propyl-4,5-dihydro-...) Show SMILES CCCC1(C)SC(NC2CCCCC2)=NC1=O |c:14| Show InChI InChI=1S/C13H22N2OS/c1-3-9-13(2)11(16)15-12(17-13)14-10-7-5-4-6-8-10/h10H,3-9H2,1-2H3,(H,14,15,16)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	55	-9.80	n/a	n/a	n/a	n/a	n/a	7.2	22
Biovitrum AB					Assay Description The 11beta-HSD1 enzyme assay was carried out in the replica plates of the compounds in reaction buffer containing substrate mixture [3H]-cortisone/NA...				J Med Chem 51: 2933-43 (2008) Article DOI: 10.1021/jm701551j BindingDB Entry DOI: 10.7270/Q2HM56Q8
					More data for this Ligand-Target Pair