BDBM23301 4-amino-7-chloroquinoline (ACQ)-based compound, 6::N-(2-aminoethyl)-7-chloroquinolin-4-amine
SMILES: NCCNc1ccnc2cc(Cl)ccc12
InChI Key: InChIKey=XBDASFGJHWAFFE-UHFFFAOYSA-N
Data: 1 Other
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Botulinum Neurotoxin Type A (Clostridium botulinum) | BDBM23301 (4-amino-7-chloroquinoline (ACQ)-based compound, 6 ...) | PDB MMDB KEGG B.MOAD GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | n/a | n/a | n/a | 7.3 | 22 |
National Cancer Institute at Frederick | Assay Description Botox A catalyzed the hydrolysis of substrate peptide between residues 11 (glutamine) and 12 (arginine), corresponding to residues 197 and 198 of SNA... | J Med Chem 50: 2127-36 (2007) Article DOI: 10.1021/jm061446e BindingDB Entry DOI: 10.7270/Q2VQ3105 | |||||||||||
More data for this Ligand-Target Pair |