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BDBM234278 5-(4-Chlorophenyl)-4-methyl-1-(pyridin-2-yl)-N-(piperidin-1-yl)-1H-pyrazole-3-carboxamide (12h)

SMILES: Cc1c(nn(c1-c1ccc(Cl)cc1)-c1ccccn1)C(=O)NN1CCCCC1

InChI Key: InChIKey=KRVDZSMMLJVZKV-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 234278   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Cannabinoid receptor 1


(Cricetulus griseus (Chinese hamster))		BDBM234278
PNG
(5-(4-Chlorophenyl)-4-methyl-1-(pyridin-2-yl)-N-(pi...)
Show SMILES Cc1c(nn(c1-c1ccc(Cl)cc1)-c1ccccn1)C(=O)NN1CCCCC1
Show InChI InChI=1S/C21H22ClN5O/c1-15-19(21(28)25-26-13-5-2-6-14-26)24-27(18-7-3-4-12-23-18)20(15)16-8-10-17(22)11-9-16/h3-4,7-12H,2,5-6,13-14H2,1H3,(H,25,28)
PDB

UniProtKB/TrEMBL

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 510n/an/an/an/an/an/a



NanChang University School of Pharmaceutical Science



Assay Description
The target compounds were evaluated using a binding assay towards the CB1 receptor expressed on the membranes of Chinese hamster ovarian (CHO) cells....

J Enzyme Inhib Med Chem 26: 222-30 (2011)


Article DOI: 10.3109/14756366.2010.491794
BindingDB Entry DOI: 10.7270/Q26D5RW8
More data for this
Ligand-Target Pair