BDBM237176 USRE46024, 21

SMILES: CC(C)c1cc(n[nH]c1=O)S(=O)(=O)c1c(Cl)cc(cc1Cl)-n1ncc(=O)[nH]c1=O

InChI Key: InChIKey=FLCRQFBWKJIFKP-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 237176   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Thyroid Hormone Receptor Beta/ Retinoid X Receptor (Homo sapiens (Human))	BDBM237176 (USRE46024, 21) Show SMILES CC(C)c1cc(n[nH]c1=O)S(=O)(=O)c1c(Cl)cc(cc1Cl)-n1ncc(=O)[nH]c1=O Show InChI InChI=1S/C16H13Cl2N5O5S/c1-7(2)9-5-13(21-22-15(9)25)29(27,28)14-10(17)3-8(4-11(14)18)23-16(26)20-12(24)6-19-23/h3-7H,1-2H3,(H,22,25)(H,20,24,26)	PDB KEGG GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	3.21E+3	n/a	n/a	7.0	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description Thirty microliters of H6-TRβ (50 nM) in 50 mM Hepes, pH 7.0, 1 mM DTT, 0.05% NP40 and 0.2 mg/ml BSA (Binding Buffer) was mixed with an equal vol...				US Patent USRE46024 (2016) BindingDB Entry DOI: 10.7270/Q24X56PH
					More data for this Ligand-Target Pair