null

SMILES: Cc1ccc(cc1)S(=O)(=O)Nc1ccccc1C

InChI Key: InChIKey=SIPGNSRRMHEOSA-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 237300   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Carbonic anhydrase 1 (Homo sapiens (Human))	BDBM237300 (4-Methyl-N-o-tolyl-benzenesulfonamide (5)) Show SMILES Cc1ccc(cc1)S(=O)(=O)Nc1ccccc1C Show InChI InChI=1S/C14H15NO2S/c1-11-7-9-13(10-8-11)18(16,17)15-14-6-4-3-5-12(14)2/h3-10,15H,1-2H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	386	-8.74	n/a	n/a	n/a	n/a	n/a	7.5	25
Ataturk University					Assay Description An applied photophysics stopped flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity [Khalifah et al., J. Biol. Chem., ...				J Enzyme Inhib Med Chem 28: 294-8 (2013) Article DOI: 10.3109/14756366.2012.658788 BindingDB Entry DOI: 10.7270/Q2TH8KKX
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM237300 (4-Methyl-N-o-tolyl-benzenesulfonamide (5)) Show SMILES Cc1ccc(cc1)S(=O)(=O)Nc1ccccc1C Show InChI InChI=1S/C14H15NO2S/c1-11-7-9-13(10-8-11)18(16,17)15-14-6-4-3-5-12(14)2/h3-10,15H,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	615	-8.47	n/a	n/a	n/a	n/a	n/a	7.5	25
Ataturk University					Assay Description An applied photophysics stopped flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity [Khalifah et al., J. Biol. Chem., ...				J Enzyme Inhib Med Chem 28: 294-8 (2013) Article DOI: 10.3109/14756366.2012.658788 BindingDB Entry DOI: 10.7270/Q2TH8KKX
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM237300 (4-Methyl-N-o-tolyl-benzenesulfonamide (5)) Show SMILES Cc1ccc(cc1)S(=O)(=O)Nc1ccccc1C Show InChI InChI=1S/C14H15NO2S/c1-11-7-9-13(10-8-11)18(16,17)15-14-6-4-3-5-12(14)2/h3-10,15H,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	407	n/a	n/a	n/a	n/a	n/a	n/a
Ataturk University					Assay Description Carbonic anhydrase activity was assayed by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion over a ...				J Enzyme Inhib Med Chem 27: 818-24 (2012) Article DOI: 10.3109/14756366.2011.617745 BindingDB Entry DOI: 10.7270/Q2G73CKP
					More data for this Ligand-Target Pair
Carbonic anhydrase 1 (Homo sapiens (Human))	BDBM237300 (4-Methyl-N-o-tolyl-benzenesulfonamide (5)) Show SMILES Cc1ccc(cc1)S(=O)(=O)Nc1ccccc1C Show InChI InChI=1S/C14H15NO2S/c1-11-7-9-13(10-8-11)18(16,17)15-14-6-4-3-5-12(14)2/h3-10,15H,1-2H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.48E+5	n/a	n/a	n/a	n/a	n/a	n/a
Ataturk University					Assay Description Carbonic anhydrase activity was assayed by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion over a ...				J Enzyme Inhib Med Chem 27: 818-24 (2012) Article DOI: 10.3109/14756366.2011.617745 BindingDB Entry DOI: 10.7270/Q2G73CKP
					More data for this Ligand-Target Pair
Carbonic anhydrase 6 (Homo sapiens (Human))	BDBM237300 (4-Methyl-N-o-tolyl-benzenesulfonamide (5)) Show SMILES Cc1ccc(cc1)S(=O)(=O)Nc1ccccc1C Show InChI InChI=1S/C14H15NO2S/c1-11-7-9-13(10-8-11)18(16,17)15-14-6-4-3-5-12(14)2/h3-10,15H,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.96E+4	n/a	n/a	n/a	n/a	n/a	n/a
Ataturk University					Assay Description Carbonic anhydrase activity was assayed by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion over a ...				J Enzyme Inhib Med Chem 27: 818-24 (2012) Article DOI: 10.3109/14756366.2011.617745 BindingDB Entry DOI: 10.7270/Q2G73CKP
					More data for this Ligand-Target Pair