BDBM238230 US9403804, 28

SMILES: CN1CCN(CC1)C1CCC(CC1)c1ccc(NC(=O)c2nc(c[nH]2)C#N)c(c1)C1=CCC(C)(C)CC1

InChI Key: InChIKey=AZBUQRFRZCNQEW-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 238230   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Macrophage colony-stimulating factor 1 receptor (c-Fms) (Mus musculus (Mouse))	BDBM238230 (US9403804, 28) Show SMILES CN1CCN(CC1)C1CCC(CC1)c1ccc(NC(=O)c2nc(c[nH]2)C#N)c(c1)C1=CCC(C)(C)CC1 |t:33,(-.58,-8.85,;-.58,-7.31,;-1.91,-6.54,;-1.91,-5,;-.58,-4.23,;.76,-5,;.76,-6.54,;-.58,-2.69,;-1.91,-1.93,;-1.91,-.38,;-.58,.38,;.76,-.38,;.76,-1.93,;-.58,1.93,;-1.91,2.69,;-1.91,4.23,;-.58,5,;-.58,6.54,;-1.91,7.31,;-1.91,8.85,;-3.24,6.54,;-3.24,5,;-4.72,4.49,;-5.61,5.78,;-4.71,7.02,;-5.2,3.03,;-5.67,1.56,;.76,4.23,;.76,2.69,;2.09,5,;2.09,6.54,;3.43,7.31,;4.76,6.54,;5.16,8.03,;6.25,6.15,;4.76,5,;3.43,4.23,)| Show InChI InChI=1S/C30H40N6O/c1-30(2)12-10-22(11-13-30)26-18-23(6-9-27(26)34-29(37)28-32-20-24(19-31)33-28)21-4-7-25(8-5-21)36-16-14-35(3)15-17-36/h6,9-10,18,20-21,25H,4-5,7-8,11-17H2,1-3H3,(H,32,33)(H,34,37)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.990	n/a	n/a	n/a	n/a	7.5	25
Janssen Pharmaceutica NV US Patent					Assay Description An autophosphorylation, fluorescence polarization competition immunoassay was used to determine the potency for c-fms inhibition exhibited by selecte...				US Patent US9403804 (2016) BindingDB Entry DOI: 10.7270/Q23T9G3C
					More data for this Ligand-Target Pair