BDBM23932 1,3-bis(trifluoromethyl)-5-[(E)-2-[4-(trifluoromethyl)phenyl]ethenyl]benzene::trans-Stilbene Derivative, 4e
SMILES: FC(F)(F)c1ccc(\C=C\c2cc(cc(c2)C(F)(F)F)C(F)(F)F)cc1
InChI Key: InChIKey=YWZOTDCCYHOIST-OWOJBTEDSA-N
Data: 3 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Aryl Hydrocarbon Receptor (AhR) (Oryctolagus cuniculus (rabbit)) | BDBM23932 (1,3-bis(trifluoromethyl)-5-[(E)-2-[4-(trifluoromet...) | PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 2.10 | -11.0 | n/a | n/a | n/a | n/a | n/a | 7.6 | 4 |
Institut Claudius Regaud | Assay Description Cytosols from rabbit liver were incubated with [3H]-TCDD and 12 concentrations of unlabeled test ligands. IC50 values were determined using the itera... | J Med Chem 48: 287-91 (2005) Article DOI: 10.1021/jm0498194 BindingDB Entry DOI: 10.7270/Q2WM1BQT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Estrogen receptor (Homo sapiens (Human)) | BDBM23932 (1,3-bis(trifluoromethyl)-5-[(E)-2-[4-(trifluoromet...) | PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institut Claudius Regaud | Assay Description Cytosols from MCF-7 cells expressed ER-alpha isoform were incubated with [3H]-estradiol and eight concentrations of unlabeled test ligands. IC50 val... | J Med Chem 48: 287-91 (2005) Article DOI: 10.1021/jm0498194 BindingDB Entry DOI: 10.7270/Q2WM1BQT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Aryl hydrocarbon receptor (Homo sapiens (Human)) | BDBM23932 (1,3-bis(trifluoromethyl)-5-[(E)-2-[4-(trifluoromet...) | PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article | 4.76E+8 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Binding affinity to aryl hydrocarbon receptor (unknown origin) | Citation and Details Article DOI: 10.1007/s00044-007-9055-2 BindingDB Entry DOI: 10.7270/Q2M32ZPJ | |||||||||||
More data for this Ligand-Target Pair |