BDBM241948 US9428466, 4'-hydroxy-2-oxo-desthiomerbarone

SMILES: Oc1ccc(NC(=O)c2c(O)[nH]c(=O)[nH]c2=O)cc1

InChI Key: InChIKey=NZECHPRNNQXBHZ-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 241948   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Xanthine dehydrogenase/oxidase (Homo sapiens (Human))	BDBM241948 (US9428466, 4'-hydroxy-2-oxo-desthiomerbarone) Show SMILES Oc1ccc(NC(=O)c2c(O)[nH]c(=O)[nH]c2=O)cc1 Show InChI InChI=1S/C11H9N3O5/c15-6-3-1-5(2-4-6)12-8(16)7-9(17)13-11(19)14-10(7)18/h1-4,15H,(H,12,16)(H3,13,14,17,18,19)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.06E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA US Patent					Assay Description Xanthine oxidase inhibition was determined using a standard fluorescence-based assay for xanthine oxidase activity (McHale A, Grimes H, Coughlan M P:...				US Patent US9428466 (2016) BindingDB Entry DOI: 10.7270/Q22J69RM
					More data for this Ligand-Target Pair
Solute carrier family 22 member 12 (Homo sapiens (Human))	BDBM241948 (US9428466, 4'-hydroxy-2-oxo-desthiomerbarone) Show SMILES Oc1ccc(NC(=O)c2c(O)[nH]c(=O)[nH]c2=O)cc1 Show InChI InChI=1S/C11H9N3O5/c15-6-3-1-5(2-4-6)12-8(16)7-9(17)13-11(19)14-10(7)18/h1-4,15H,(H,12,16)(H3,13,14,17,18,19)	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA US Patent					Assay Description URAT1 (SLC22A12) activity was evaluated in a cellular uptake assay using a 96-well plate with stably transfected URAT-1/CHO cells. 3H-orotate was use...				US Patent US9428466 (2016) BindingDB Entry DOI: 10.7270/Q22J69RM
					More data for this Ligand-Target Pair