Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Solute carrier family 22 member 12' and Ligand = 'BDBM241948'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Solute carrier family 22 member 12 (Homo sapiens (Human))	BDBM241948 (US9428466, 4'-hydroxy-2-oxo-desthiomerbarone) Show SMILES Oc1ccc(NC(=O)c2c(O)[nH]c(=O)[nH]c2=O)cc1 Show InChI InChI=1S/C11H9N3O5/c15-6-3-1-5(2-4-6)12-8(16)7-9(17)13-11(19)14-10(7)18/h1-4,15H,(H,12,16)(H3,13,14,17,18,19)	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA US Patent					Assay Description URAT1 (SLC22A12) activity was evaluated in a cellular uptake assay using a 96-well plate with stably transfected URAT-1/CHO cells. 3H-orotate was use...				US Patent US9428466 (2016) BindingDB Entry DOI: 10.7270/Q22J69RM
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