BDBM242586 (R)-N-(1-(Isoindolin-2-yl)propan-2-yl)- 4-(5-(trifluoromethyl)-1,2,4-oxadiazol- 3-yl)benzamide::US10053434, 3

SMILES: C[C@H](CN1Cc2ccccc2C1)NC(=O)c1ccc(cc1)-c1noc(n1)C(F)(F)F

InChI Key: InChIKey=GAKKVPPZDBDLED-CYBMUJFWSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 242586   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
HDAC4 (Homo sapiens (Human))	BDBM242586 ((R)-N-(1-(Isoindolin-2-yl)propan-2-yl)- 4-(5-(trif...) Show SMILES C[C@H](CN1Cc2ccccc2C1)NC(=O)c1ccc(cc1)-c1noc(n1)C(F)(F)F |r| Show InChI InChI=1S/C21H19F3N4O2/c1-13(10-28-11-16-4-2-3-5-17(16)12-28)25-19(29)15-8-6-14(7-9-15)18-26-20(30-27-18)21(22,23)24/h2-9,13H,10-12H2,1H3,(H,25,29)/t13-/m1/s1	PDB GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	39	n/a	n/a	n/a	n/a	n/a	n/a
CHDI FOUNDATION, INC. US Patent					Assay Description 5 μL of each solution of 1:20 diluted compound from above was transferred to a clear bottomed, black, 384-well assay plate using the Bravo or th...				US Patent US10053434 (2018) BindingDB Entry DOI: 10.7270/Q2MG7RJZ
					More data for this Ligand-Target Pair