BDBM243040 N-[(2-Amino-4-oxo-4,7-dihydro-3H-pyrrolo[2,3-d]pyrimidin-5-yl)methyl]-5-methylthiophene-2-carboxamide (7)

SMILES: Cc1ccc(s1)C(=O)NCc1c[nH]c2nc(N)[nH]c(=O)c12

InChI Key: InChIKey=YTLFBBKWWYJIKU-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 243040   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM243040 (N-[(2-Amino-4-oxo-4,7-dihydro-3H-pyrrolo[2,3-d]pyr...) Show SMILES Cc1ccc(s1)C(=O)NCc1c[nH]c2nc(N)[nH]c(=O)c12 Show InChI InChI=1S/C13H13N5O2S/c1-6-2-3-8(21-6)11(19)16-5-7-4-15-10-9(7)12(20)18-13(14)17-10/h2-4H,5H2,1H3,(H,16,19)(H4,14,15,17,18,20)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.60E+4	n/a	n/a	n/a	n/a	n/a	22
Ankara University					Assay Description Kinase activity (Src-family kinases, Hck, Lyn, Fyn, and c-Src) and the effect of the molecules were determined by ProFluor Src-Family Kinase Assay Ki...				J Enzyme Inhib Med Chem 28: 1080-7 (2013) Article DOI: 10.3109/14756366.2012.715288 BindingDB Entry DOI: 10.7270/Q2KD1WTX
					More data for this Ligand-Target Pair