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SMILES: C[C@H](CN1CC2CCC(C2)C1)NC(=O)c1ccc(cc1)-c1noc(n1)C(F)(F)F

InChI Key: InChIKey=KLHHKVSPGWUPSV-IYXRBSQSSA-N

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   Substructure
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 243183   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Histone deacetylase 4 [648-1032]


(Homo sapiens (Human))		BDBM243183
PNG
(N-((R)-1-(3-Azabicyclo[3.2.1]octan-3- yl)propan-2-...)
Show SMILES C[C@H](CN1CC2CCC(C2)C1)NC(=O)c1ccc(cc1)-c1noc(n1)C(F)(F)F |r|
Show InChI InChI=1S/C20H23F3N4O2/c1-12(9-27-10-13-2-3-14(8-13)11-27)24-18(28)16-6-4-15(5-7-16)17-25-19(29-26-17)20(21,22)23/h4-7,12-14H,2-3,8-11H2,1H3,(H,24,28)/t12-,13?,14?/m1/s1
PDB

UniProtKB/SwissProt

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PC cid
PC sid
UniChem
US Patent
n/an/a 7n/an/an/an/an/an/a



CHDI FOUNDATION, INC.

US Patent


Assay Description
5 μL of each solution of 1:20 diluted compound from above was transferred to a clear bottomed, black, 384-well assay plate using the Bravo or th...

US Patent US10053434 (2018)


BindingDB Entry DOI: 10.7270/Q2MG7RJZ
More data for this
Ligand-Target Pair