BindingDB logo
myBDB logout

null

SMILES: Cc1ccnc(Nc2cccc(c2)-c2cnc(o2)N2CCNC(=O)C22CCCC2)n1

InChI Key: InChIKey=WANSKCOCWJIGLK-UHFFFAOYSA-N

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 243353   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Tyrosine-protein kinase SYK


(Homo sapiens (Human))		BDBM243353
PNG
(6-{5-[3-(4-Methyl- pyrimidin-2-ylamino)- phenyl]-o...)
Show SMILES Cc1ccnc(Nc2cccc(c2)-c2cnc(o2)N2CCNC(=O)C22CCCC2)n1
Show InChI InChI=1S/C22H24N6O2/c1-15-7-10-24-20(26-15)27-17-6-4-5-16(13-17)18-14-25-21(30-18)28-12-11-23-19(29)22(28)8-2-3-9-22/h4-7,10,13-14H,2-3,8-9,11-12H2,1H3,(H,23,29)(H,24,26,27)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a<500n/an/an/an/a7.825



AB SCIENCE

US Patent


Assay Description
SYK kinase was purified as a full length protein in a baculovirus system near homogeneity. All kinase assays were performed with the Kinase TK (tyros...

US Patent US10053455 (2018)


BindingDB Entry DOI: 10.7270/Q27946PV
More data for this
Ligand-Target Pair