null
SMILES: CC1(C)CC(C1)C(Nc1cnc(nc1)-n1cc(cn1)C(F)(F)F)c1ccc(cc1)C(=O)NCCC(O)=O
InChI Key: InChIKey=YDXHIJKYXAXQTE-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Pro-glucagon (Homo sapiens (Human)) | BDBM2437 (US8507533, 157) | Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 5.55 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. US Patent | Assay Description The Glucagon SPA assay is used to determine the ability of test compounds to block the binding of glucagon-cex to the glucagon receptors. | US Patent US8507533 (2013) BindingDB Entry DOI: 10.7270/Q23R0RGH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glucagon receptor (Homo sapiens (Human)) | BDBM2437 (US8507533, 157) | PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | PubMed | 5.60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. Curated by ChEMBL | Assay Description Displacement of [125I]-glucagon from human glucagon receptor expressed in Chem-1 cell membranes after 6 to 10 hrs by scintillation proximity assay | Bioorg Med Chem Lett 25: 4057-64 (2015) BindingDB Entry DOI: 10.7270/Q2HM5B7N | |||||||||||
More data for this Ligand-Target Pair |