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SMILES: Cc1c(sc2ccccc12)N(Cc1ccc2OC(F)(F)Oc2c1)S(=O)(=O)c1ccc(cc1)C(O)=O

InChI Key: InChIKey=BPPYVJCWWHDTLJ-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 248605   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Transient receptor potential M8 protein


(Canis lupus familiaris (Dog))		BDBM248605
PNG
(US9434711, 524)
Show SMILES Cc1c(sc2ccccc12)N(Cc1ccc2OC(F)(F)Oc2c1)S(=O)(=O)c1ccc(cc1)C(O)=O
Show InChI InChI=1S/C24H17F2NO6S2/c1-14-18-4-2-3-5-21(18)34-22(14)27(35(30,31)17-9-7-16(8-10-17)23(28)29)13-15-6-11-19-20(12-15)33-24(25,26)32-19/h2-12H,13H2,1H3,(H,28,29)
PDB

KEGG

UniProtKB/TrEMBL

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 2n/an/an/an/an/a37



Janssen Pharmaceutica, N.V.

US Patent


Assay Description
The functional activity of compounds of the formula (I) was determined by measuring changes in intracellular calcium concentration using a Ca2+-sensi...

US Patent US9434711 (2016)


BindingDB Entry DOI: 10.7270/Q2H41QB6
More data for this
Ligand-Target Pair