Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Transient receptor potential M8 protein' and Ligand = 'BDBM248605'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Transient receptor potential M8 protein (Canis lupus familiaris (Dog))	BDBM248605 (US9434711, 524) Show SMILES Cc1c(sc2ccccc12)N(Cc1ccc2OC(F)(F)Oc2c1)S(=O)(=O)c1ccc(cc1)C(O)=O Show InChI InChI=1S/C24H17F2NO6S2/c1-14-18-4-2-3-5-21(18)34-22(14)27(35(30,31)17-9-7-16(8-10-17)23(28)29)13-15-6-11-19-20(12-15)33-24(25,26)32-19/h2-12H,13H2,1H3,(H,28,29)	PDB KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	37
Janssen Pharmaceutica, N.V. US Patent					Assay Description The functional activity of compounds of the formula (I) was determined by measuring changes in intracellular calcium concentration using a Ca2+-sensi...				US Patent US9434711 (2016) BindingDB Entry DOI: 10.7270/Q2H41QB6
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