BDBM2494 (+/-)-4-Hydroxy.6-phenyl-3-[phenyl(phenylthio)methyl]-2H-pyran-2-one::4-hydroxy-6-phenyl-3-[phenyl(phenylsulfanyl)methyl]-2H-pyran-2-one::4-hydroxy-6-phenyl-pyranylthiomethane 24::C-3-substituted Pyran-2-one 3

SMILES: Oc1cc(oc(=O)c1C(Sc1ccccc1)c1ccccc1)-c1ccccc1

InChI Key: InChIKey=LVOUHVQQFFTPTD-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 2494   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
HIV-1 Protease (Human immunodeficiency virus type 1)	BDBM2494 ((+/-)-4-Hydroxy.6-phenyl-3-[phenyl(phenylthio)meth...) Show SMILES Oc1cc(oc(=O)c1C(Sc1ccccc1)c1ccccc1)-c1ccccc1 Show InChI InChI=1S/C24H18O3S/c25-20-16-21(17-10-4-1-5-11-17)27-24(26)22(20)23(18-12-6-2-7-13-18)28-19-14-8-3-9-15-19/h1-16,23,25H	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	780	n/a	n/a	n/a	n/a	4.7	37
Parke-Davis Pharmaceutical Research					Assay Description For determination of IC50 values, HIV-1 protease was added to assay buffer containing inhibitor and the substrate (H-His-Lys-Ala-Arg-Val-Leu- (p-NO2)...				Bioorg Med Chem 4: 1401-10 (1996) Article DOI: 10.1016/j.bmcl.2004.12.068 BindingDB Entry DOI: 10.7270/Q2PZ571Q
					More data for this Ligand-Target Pair
HIV-1 Protease (Human immunodeficiency virus type 1)	BDBM2494 ((+/-)-4-Hydroxy.6-phenyl-3-[phenyl(phenylthio)meth...) Show SMILES Oc1cc(oc(=O)c1C(Sc1ccccc1)c1ccccc1)-c1ccccc1 Show InChI InChI=1S/C24H18O3S/c25-20-16-21(17-10-4-1-5-11-17)27-24(26)22(20)23(18-12-6-2-7-13-18)28-19-14-8-3-9-15-19/h1-16,23,25H	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	780	n/a	n/a	n/a	n/a	4.7	37
Parke-Davis Pharmaceutical Research					Assay Description For determination of IC50 values, HIV-1 protease was added to assay buffer containing inhibitor and the substrate (H-His-Lys-Ala-Arg-Val-Leu- (p-NO2)...				J Med Chem 38: 898-905 (1995) Article DOI: 10.1021/jm00006a007 BindingDB Entry DOI: 10.7270/Q2348HJB
					More data for this Ligand-Target Pair