BDBM249764 US9447038, 192

SMILES: CCCN(Cc1ccc(SCCN2C(=O)CCC2=O)c(OC)c1)C(CC(O)=O)c1ccc(Cl)c(Cl)c1

InChI Key: InChIKey=PREGNEPYLWKHIM-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 249764   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-X-C motif chemokine 10 (CXCL10) (Homo sapiens (Human))	BDBM249764 (US9447038, 192) Show SMILES CCCN(Cc1ccc(SCCN2C(=O)CCC2=O)c(OC)c1)C(CC(O)=O)c1ccc(Cl)c(Cl)c1 Show InChI InChI=1S/C26H30Cl2N2O5S/c1-3-10-29(21(15-26(33)34)18-5-6-19(27)20(28)14-18)16-17-4-7-23(22(13-17)35-2)36-12-11-30-24(31)8-9-25(30)32/h4-7,13-14,21H,3,8-12,15-16H2,1-2H3,(H,33,34)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	25
Sanofi US Patent					Assay Description The composition of the binding assay buffer is determined in a course of detailed optimization procedure. This resulted in a binding assay buffer con...				US Patent US9447038 (2016) BindingDB Entry DOI: 10.7270/Q29G5KQK
					More data for this Ligand-Target Pair