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SMILES: Nc1ccccc1NC(=O)c1ccccn1

InChI Key: InChIKey=XIQCXQUJFNTCCK-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 25244   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Histone deacetylase 1


(Homo sapiens (Human))		BDBM25244
PNG
(N-(2-aminophenyl)pyridine-2-carboxamide | benzamid...)
Show SMILES Nc1ccccc1NC(=O)c1ccccn1
Show InChI InChI=1S/C12H11N3O/c13-9-5-1-2-6-10(9)15-12(16)11-7-3-4-8-14-11/h1-8H,13H2,(H,15,16)
PDB
MMDB

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PC cid
PC sid
UniChem
Article
PubMed
n/an/a 2.46E+3n/an/an/an/a8.022



AstraZeneca



Assay Description
The Fluor-de-Lys HDAC activity assay kit (Biomol) was used. Affinity purified recombinant HDAC1 enzyme was incubated with acetylated histone H4 pepti...

Bioorg Med Chem Lett 18: 2580-4 (2008)


Article DOI: 10.1016/j.bmcl.2008.03.041
BindingDB Entry DOI: 10.7270/Q23T9FJS
More data for this
Ligand-Target Pair