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SMILES: C[C@@H]1Cn2c(CCO1)c(nc2-c1ccc(OC(F)(F)F)c(Cl)c1)-c1ccnc(C)c1

InChI Key: InChIKey=UQKOMQWXYNDRGB-CYBMUJFWSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 252756   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Metabotropic glutamate receptor 2


(Homo sapiens (Human))		BDBM252756
PNG
(US9458176, 153)
Show SMILES C[C@@H]1Cn2c(CCO1)c(nc2-c1ccc(OC(F)(F)F)c(Cl)c1)-c1ccnc(C)c1 |r|
Show InChI InChI=1S/C21H19ClF3N3O2/c1-12-9-14(5-7-26-12)19-17-6-8-29-13(2)11-28(17)20(27-19)15-3-4-18(16(22)10-15)30-21(23,24)25/h3-5,7,9-10,13H,6,8,11H2,1-2H3/t13-/m1/s1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 3n/an/an/an/an/a25



Eisai R&D Management Co., Ltd.

US Patent


Assay Description
The frozen cell membrane fraction prepared as described above was thawed before use, and the resultant was diluted with a buffer for a binding assay ...

US Patent US9458176 (2016)


BindingDB Entry DOI: 10.7270/Q2PK0F3D
More data for this
Ligand-Target Pair