BDBM26040 5-{2-[4-(aminomethyl)phenyl]-5-(pyridin-4-yl)-1H-imidazol-4-yl}-2-chlorophenol::CHEMBL200320::Rhodamine green labeled 5-{2-[4-(aminomethyl)phenyl]-5-pyridin-4-yl-1H-imidazol-4-yl}-2-chlorophenol::Rhodamine green labeled ligand

SMILES: NCc1ccc(cc1)-c1nc(c([nH]1)-c1ccc(Cl)c(O)c1)-c1ccncc1

InChI Key: InChIKey=UOHHVCYLYIQXFG-UHFFFAOYSA-N

Data: 1 IC50  1 Kd

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 26040   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase B-raf (Homo sapiens (Human))	BDBM26040 (5-{2-[4-(aminomethyl)phenyl]-5-(pyridin-4-yl)-1H-i...) Show SMILES NCc1ccc(cc1)-c1nc(c([nH]1)-c1ccc(Cl)c(O)c1)-c1ccncc1 Show InChI InChI=1S/C21H17ClN4O/c22-17-6-5-16(11-18(17)27)20-19(14-7-9-24-10-8-14)25-21(26-20)15-3-1-13(12-23)2-4-15/h1-11,27H,12,23H2,(H,25,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition bRaf kinase activity				Bioorg Med Chem Lett 16: 378-81 (2005) Article DOI: 10.1016/j.bmcl.2005.09.072 BindingDB Entry DOI: 10.7270/Q2Z038Z9
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase B-raf (Homo sapiens (Human))	BDBM26040 (5-{2-[4-(aminomethyl)phenyl]-5-(pyridin-4-yl)-1H-i...) Show SMILES NCc1ccc(cc1)-c1nc(c([nH]1)-c1ccc(Cl)c(O)c1)-c1ccncc1 Show InChI InChI=1S/C21H17ClN4O/c22-17-6-5-16(11-18(17)27)20-19(14-7-9-24-10-8-14)25-21(26-20)15-3-1-13(12-23)2-4-15/h1-11,27H,12,23H2,(H,25,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	5.30	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Pharmaceuticals Curated by ChEMBL					Assay Description Binding affinity at bRaf kinase in fluorescent ligand displacement assay				Bioorg Med Chem Lett 16: 378-81 (2005) Article DOI: 10.1016/j.bmcl.2005.09.072 BindingDB Entry DOI: 10.7270/Q2Z038Z9
					More data for this Ligand-Target Pair