BindingDB PrimarySearch

BDBM26267 RO-154513::Ro15-4513::[3H]Ro15-4513::ethyl 12-azido-8-methyl-9-oxo-2,4,8-triazatricyclo[8.4.0.0^{2,6}]tetradeca-1(10),3,5,11,13-pentaene-5-carboxylate

SMILES: CCOC(=O)c1ncn-2c1CN(C)C(=O)c1cc(ccc-21)N=[N+]=[N-]

InChI Key: InChIKey=CFSOJZTUTOQNIA-UHFFFAOYSA-N

Data: 35 KI 1 EC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 36 hits for monomerid = 26267
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
GABA receptor alpha-5/beta-3/gamma-2 subunit (Homo sapiens (Human))	BDBM26267 (RO-154513 \| Ro15-4513 \| [3H]Ro15-4513 \| ethyl 12-a...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	0.270	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Wisconsin-Milwaukee Curated by ChEMBL					Assay Description Binding affinity for Gamma-aminobutyric-acid A receptor alpha5-beta3-gamma2				J Med Chem 41: 4130-42 (1998) Article DOI: 10.1021/jm980317y BindingDB Entry DOI: 10.7270/Q2W37VFJ
University of Wisconsin-Milwaukee Curated by ChEMBL					More data for this Ligand-Target Pair
GABA receptor alpha-5/beta-3/gamma-2 subunit (Homo sapiens (Human))	BDBM26267 (RO-154513 \| Ro15-4513 \| [3H]Ro15-4513 \| ethyl 12-a...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PubMed	0.300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Wisconsin-Milwaukee Curated by ChEMBL					Assay Description Binding affinity for human recombinant gamma-aminobutyric-acid (GABA) A receptor alpha-5-beta-3-gamma-2				J Med Chem 43: 71-95 (2000) BindingDB Entry DOI: 10.7270/Q2W37X0J
University of Wisconsin-Milwaukee Curated by ChEMBL					More data for this Ligand-Target Pair
GABA receptor alpha-5/beta-3/gamma-2 subunit (Homo sapiens (Human))	BDBM26267 (RO-154513 \| Ro15-4513 \| [3H]Ro15-4513 \| ethyl 12-a...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	0.300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Wisconsin-Milwaukee Curated by ChEMBL					Assay Description In vitro binding affinity for human GABA-A receptor alpha5-beta3-gamma2 subunits expressed in L(tk-) cell membranes				J Med Chem 46: 5567-70 (2003) Article DOI: 10.1021/jm034164c BindingDB Entry DOI: 10.7270/Q2R78DNC
University of Wisconsin-Milwaukee Curated by ChEMBL					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-5 (GABA(A)) (Homo sapiens (Human))	BDBM26267 (RO-154513 \| Ro15-4513 \| [3H]Ro15-4513 \| ethyl 12-a...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PubMed	0.700	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Research Laboratories Curated by PDSP K_i Database									Mol Pharmacol 43: 970-5 (1993) BindingDB Entry DOI: 10.7270/Q2ZS2V1S
					More data for this Ligand-Target Pair
GABA receptor alpha-3/beta-3/gamma-2 subunit (Homo sapiens (Human))	BDBM26267 (RO-154513 \| Ro15-4513 \| [3H]Ro15-4513 \| ethyl 12-a...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	2.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Wisconsin-Milwaukee Curated by ChEMBL					Assay Description Binding affinity against alpha3-beta3-gamma2 GABAA/BzR receptor subtype.				J Med Chem 41: 4130-42 (1998) Article DOI: 10.1021/jm980317y BindingDB Entry DOI: 10.7270/Q2W37VFJ
University of Wisconsin-Milwaukee Curated by ChEMBL					More data for this Ligand-Target Pair
GABA receptor alpha-3/beta-3/gamma-2 subunit (Homo sapiens (Human))	BDBM26267 (RO-154513 \| Ro15-4513 \| [3H]Ro15-4513 \| ethyl 12-a...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PubMed	2.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Wisconsin-Milwaukee Curated by ChEMBL					Assay Description Binding affinity for human recombinant gamma-aminobutyric-acid (GABA) A receptor alpha-3-beta-3-gamma-2				J Med Chem 43: 71-95 (2000) BindingDB Entry DOI: 10.7270/Q2W37X0J
University of Wisconsin-Milwaukee Curated by ChEMBL					More data for this Ligand-Target Pair
GABA receptor alpha-3/beta-2/gamma-2 subunit (Homo sapiens (Human))	BDBM26267 (RO-154513 \| Ro15-4513 \| [3H]Ro15-4513 \| ethyl 12-a...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	2.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Wisconsin-Milwaukee Curated by ChEMBL					Assay Description Binding affinity for human GABA-A receptor alpha-3-beta-2-gamma-2 expressed in L(tk-) cell membranes				J Med Chem 39: 1928-34 (1996) Article DOI: 10.1021/jm950887n BindingDB Entry DOI: 10.7270/Q2K35SR6
University of Wisconsin-Milwaukee Curated by ChEMBL					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-1 (Homo sapiens (Human))	BDBM26267 (RO-154513 \| Ro15-4513 \| [3H]Ro15-4513 \| ethyl 12-a...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PubMed	2.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Research Laboratories Curated by PDSP K_i Database									Mol Pharmacol 49: 253-9 (1996) BindingDB Entry DOI: 10.7270/Q2639N8C
					More data for this Ligand-Target Pair
GABA receptor alpha-2/beta-3/gamma-2 subunit (Homo sapiens (Human))	BDBM26267 (RO-154513 \| Ro15-4513 \| [3H]Ro15-4513 \| ethyl 12-a...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	2.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Wisconsin-Milwaukee Curated by ChEMBL					Assay Description In vitro binding affinity for human GABA-A receptor alpha2-beta3-gamma2 subunits expressed in L(tk-) cell membranes				J Med Chem 46: 5567-70 (2003) Article DOI: 10.1021/jm034164c BindingDB Entry DOI: 10.7270/Q2R78DNC
University of Wisconsin-Milwaukee Curated by ChEMBL					More data for this Ligand-Target Pair
GABA receptor alpha-2/beta-2/gamma-2 subunit (Homo sapiens (Human))	BDBM26267 (RO-154513 \| Ro15-4513 \| [3H]Ro15-4513 \| ethyl 12-a...) Show SMILES Show InChI	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	2.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Wisconsin-Milwaukee Curated by ChEMBL					Assay Description Binding affinity for human GABA-A receptor alpha-2-beta-2-gamma-2 expressed in L(tk-) cell membranes				J Med Chem 39: 1928-34 (1996) Article DOI: 10.1021/jm950887n BindingDB Entry DOI: 10.7270/Q2K35SR6
University of Wisconsin-Milwaukee Curated by ChEMBL					More data for this Ligand-Target Pair
GABA receptor alpha-2/beta-3/gamma-2 subunit (Homo sapiens (Human))	BDBM26267 (RO-154513 \| Ro15-4513 \| [3H]Ro15-4513 \| ethyl 12-a...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PubMed	2.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Wisconsin-Milwaukee Curated by ChEMBL					Assay Description Binding affinity to human recombinant gamma-aminobutyric-acid (GABA) A receptor alpha-2-beta-3-gamma-2				J Med Chem 43: 71-95 (2000) BindingDB Entry DOI: 10.7270/Q2W37X0J
University of Wisconsin-Milwaukee Curated by ChEMBL					More data for this Ligand-Target Pair
GABA receptor alpha-2/beta-3/gamma-2 subunit (Homo sapiens (Human))	BDBM26267 (RO-154513 \| Ro15-4513 \| [3H]Ro15-4513 \| ethyl 12-a...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	2.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Wisconsin-Milwaukee Curated by ChEMBL					Assay Description Binding affinity of the compound tested against alpha2-beta3-gamma2 GABAA/BzR receptor subtype.				J Med Chem 41: 4130-42 (1998) Article DOI: 10.1021/jm980317y BindingDB Entry DOI: 10.7270/Q2W37VFJ
University of Wisconsin-Milwaukee Curated by ChEMBL					More data for this Ligand-Target Pair
GABA A Alpha4Beta2Gamma2 (Homo sapiens (Human))	BDBM26267 (RO-154513 \| Ro15-4513 \| [3H]Ro15-4513 \| ethyl 12-a...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	2.62	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
CoCensys, Inc. Curated by PDSP K_i Database									Eur J Pharmacol 291: 319-25 (1995) Article DOI: 10.1016/0922-4106(95)90072-1 BindingDB Entry DOI: 10.7270/Q2JD4VB2
CoCensys, Inc. Curated by PDSP K_i Database					More data for this Ligand-Target Pair
GABAA Receptor, alpha-4, beta-2, gamma-2 (Homo sapiens (Human))	BDBM26267 (RO-154513 \| Ro15-4513 \| [3H]Ro15-4513 \| ethyl 12-a...) Show SMILES Show InChI	PDB KEGG DrugBank GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	3.10	-11.5	n/a	n/a	n/a	n/a	n/a	7.4	22
University of Wisconsin at Madison					Assay Description Membrane homogenates were incubated at room temperature with a sub-Kd concentration of radioligand in the absence or presence of seven different conc...				J Med Chem 51: 7243-52 (2008) Article DOI: 10.1021/jm800889m BindingDB Entry DOI: 10.7270/Q2R78CJM
University of Wisconsin at Madison					More data for this Ligand-Target Pair
GABA-A receptor; alpha-1/beta-2/gamma-2 (Homo sapiens (Human))	BDBM26267 (RO-154513 \| Ro15-4513 \| [3H]Ro15-4513 \| ethyl 12-a...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	3.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Wisconsin-Milwaukee Curated by ChEMBL					Assay Description Binding affinity for human GABA-A receptor alpha-1-beta-2-gamma-2 expressed in L(tk-) cell membranes				J Med Chem 39: 1928-34 (1996) Article DOI: 10.1021/jm950887n BindingDB Entry DOI: 10.7270/Q2K35SR6
University of Wisconsin-Milwaukee Curated by ChEMBL					More data for this Ligand-Target Pair
GABA receptor alpha-1/beta-3/gamma-2 subunit (Homo sapiens (Human))	BDBM26267 (RO-154513 \| Ro15-4513 \| [3H]Ro15-4513 \| ethyl 12-a...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	3.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Wisconsin-Milwaukee Curated by ChEMBL					Assay Description Binding affinity against alpha1-beta3-gamma2 GABAA/BzR receptor subtype.				J Med Chem 41: 4130-42 (1998) Article DOI: 10.1021/jm980317y BindingDB Entry DOI: 10.7270/Q2W37VFJ
University of Wisconsin-Milwaukee Curated by ChEMBL					More data for this Ligand-Target Pair
GABA receptor alpha-1/beta-3/gamma-2 subunit (Homo sapiens (Human))	BDBM26267 (RO-154513 \| Ro15-4513 \| [3H]Ro15-4513 \| ethyl 12-a...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PubMed	3.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Wisconsin-Milwaukee Curated by ChEMBL					Assay Description Binding affinity for human recombinant gamma-aminobutyric-acid (GABA) A receptor alpha-1-beta-3-gamma-2				J Med Chem 43: 71-95 (2000) BindingDB Entry DOI: 10.7270/Q2W37X0J
University of Wisconsin-Milwaukee Curated by ChEMBL					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor (GABA(A)) subunit alpha-4 (Rattus norvegicus (Rat))	BDBM26267 (RO-154513 \| Ro15-4513 \| [3H]Ro15-4513 \| ethyl 12-a...) Show SMILES Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	3.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Diabetes, Digestive, and Kidney Diseases Curated by PDSP K_i Database									Neuropharmacology 35: 1307-14 (1996) Article DOI: 10.1016/s0028-3908(96)00054-8 BindingDB Entry DOI: 10.7270/Q28S4NF7
					More data for this Ligand-Target Pair
GABA receptor alpha-6/beta-3/gamma-2 subunit (Homo sapiens (Human))	BDBM26267 (RO-154513 \| Ro15-4513 \| [3H]Ro15-4513 \| ethyl 12-a...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	3.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Wisconsin-Milwaukee Curated by ChEMBL					Assay Description In vitro binding affinity for human GABA-A receptor alpha6-beta3-gamma2 subunits expressed in L(tk-) cell membranes				J Med Chem 46: 5567-70 (2003) Article DOI: 10.1021/jm034164c BindingDB Entry DOI: 10.7270/Q2R78DNC
University of Wisconsin-Milwaukee Curated by ChEMBL					More data for this Ligand-Target Pair
GABA A receptor alpha-6/beta-2/gamma-2 (Homo sapiens (Human))	BDBM26267 (RO-154513 \| Ro15-4513 \| [3H]Ro15-4513 \| ethyl 12-a...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	3.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Wisconsin-Milwaukee Curated by ChEMBL					Assay Description Binding affinity for human GABA-A receptor alpha-6-beta-2-gamma-2 expressed in L(tk-) cell membranes				J Med Chem 39: 1928-34 (1996) Article DOI: 10.1021/jm950887n BindingDB Entry DOI: 10.7270/Q2K35SR6
University of Wisconsin-Milwaukee Curated by ChEMBL					More data for this Ligand-Target Pair
GABA receptor alpha-6/beta-3/gamma-2 subunit (Homo sapiens (Human))	BDBM26267 (RO-154513 \| Ro15-4513 \| [3H]Ro15-4513 \| ethyl 12-a...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PubMed	3.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Wisconsin-Milwaukee Curated by ChEMBL					Assay Description Binding affinity for human recombinant gamma-aminobutyric-acid (GABA) A receptor alpha-6-beta-3-gamma-2				J Med Chem 43: 71-95 (2000) BindingDB Entry DOI: 10.7270/Q2W37X0J
University of Wisconsin-Milwaukee Curated by ChEMBL					More data for this Ligand-Target Pair
GABA receptor alpha-6/beta-3/gamma-2 subunit (Homo sapiens (Human))	BDBM26267 (RO-154513 \| Ro15-4513 \| [3H]Ro15-4513 \| ethyl 12-a...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	3.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Wisconsin-Milwaukee Curated by ChEMBL					Assay Description Binding affinity against Gamma-aminobutyric-acid A receptor alpha6-beta3-gamma2				J Med Chem 41: 4130-42 (1998) Article DOI: 10.1021/jm980317y BindingDB Entry DOI: 10.7270/Q2W37VFJ
University of Wisconsin-Milwaukee Curated by ChEMBL					More data for this Ligand-Target Pair
GABAA Receptor, alpha-6, beta-2, gamma-2 (Homo sapiens (Human))	BDBM26267 (RO-154513 \| Ro15-4513 \| [3H]Ro15-4513 \| ethyl 12-a...) Show SMILES Show InChI	PDB KEGG DrugBank GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	5.10	-11.2	n/a	n/a	n/a	n/a	n/a	7.4	22
University of Wisconsin at Madison					Assay Description Membrane homogenates were incubated at room temperature with a sub-Kd concentration of radioligand in the absence or presence of seven different conc...				J Med Chem 51: 7243-52 (2008) Article DOI: 10.1021/jm800889m BindingDB Entry DOI: 10.7270/Q2R78CJM
University of Wisconsin at Madison					More data for this Ligand-Target Pair
GABA A receptor alpha-6/beta-2/gamma-2 (RAT)	BDBM26267 (RO-154513 \| Ro15-4513 \| [3H]Ro15-4513 \| ethyl 12-a...) Show SMILES Show InChI	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	5.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Diabetes, Digestive, and Kidney Diseases Curated by PDSP K_i Database									Neuropharmacology 35: 1307-14 (1996) Article DOI: 10.1016/s0028-3908(96)00054-8 BindingDB Entry DOI: 10.7270/Q28S4NF7
					More data for this Ligand-Target Pair
GABA A receptor alpha-6/beta-2/gamma-2 (Homo sapiens (Human))	BDBM26267 (RO-154513 \| Ro15-4513 \| [3H]Ro15-4513 \| ethyl 12-a...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	5.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Upjohn Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]Ro-154513 from GABA-A receptor alpha-6-beta-2-gamma-2 subunits expressed in Sf9 cells				J Med Chem 39: 158-75 (1996) Article DOI: 10.1021/jm940765f BindingDB Entry DOI: 10.7270/Q2PZ57WX
Upjohn Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
GABA A receptor alpha-6/beta-2/gamma-2 (Homo sapiens (Human))	BDBM26267 (RO-154513 \| Ro15-4513 \| [3H]Ro15-4513 \| ethyl 12-a...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PubMed	5.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Upjohn Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]-Ro- 15-4513 from alpha-6-beta-2-gamma-2 GABA-A receptor subunits expressed in Sf9 cell membranes				J Med Chem 37: 758-68 (1994) BindingDB Entry DOI: 10.7270/Q27W6B8R
Upjohn Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
GABA A Alpha4Beta2Gamma2 (Homo sapiens (Human))	BDBM26267 (RO-154513 \| Ro15-4513 \| [3H]Ro15-4513 \| ethyl 12-a...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	5.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University Clinic for Psychiatry Curated by PDSP K_i Database									Eur J Pharmacol 304: 155-62 (1996) Article DOI: 10.1016/0014-2999(96)00088-x BindingDB Entry DOI: 10.7270/Q2HD7T6P
					More data for this Ligand-Target Pair
GABA A receptor alpha-3/beta-2/gamma-2 (Homo sapiens (Human))	BDBM26267 (RO-154513 \| Ro15-4513 \| [3H]Ro15-4513 \| ethyl 12-a...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PubMed	7.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Research Laboratories Curated by PDSP K_i Database									Mol Pharmacol 43: 970-5 (1993) BindingDB Entry DOI: 10.7270/Q2ZS2V1S
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-1 (Homo sapiens (Human))	BDBM26267 (RO-154513 \| Ro15-4513 \| [3H]Ro15-4513 \| ethyl 12-a...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	8.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University Clinic for Psychiatry Curated by PDSP K_i Database									Eur J Pharmacol 304: 155-62 (1996) Article DOI: 10.1016/0014-2999(96)00088-x BindingDB Entry DOI: 10.7270/Q2HD7T6P
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-1 (Homo sapiens (Human))	BDBM26267 (RO-154513 \| Ro15-4513 \| [3H]Ro15-4513 \| ethyl 12-a...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PubMed	10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Research Laboratories Curated by PDSP K_i Database									Mol Pharmacol 43: 970-5 (1993) BindingDB Entry DOI: 10.7270/Q2ZS2V1S
					More data for this Ligand-Target Pair
GABA A Alpha2Beta1Gamma2 (Homo sapiens (Human))	BDBM26267 (RO-154513 \| Ro15-4513 \| [3H]Ro15-4513 \| ethyl 12-a...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PubMed	10.4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Research Laboratories Curated by PDSP K_i Database									Mol Pharmacol 43: 970-5 (1993) BindingDB Entry DOI: 10.7270/Q2ZS2V1S
					More data for this Ligand-Target Pair
GABA A Alpha4Beta2Gamma2 (Homo sapiens (Human))	BDBM26267 (RO-154513 \| Ro15-4513 \| [3H]Ro15-4513 \| ethyl 12-a...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	10.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University Clinic for Psychiatry Curated by PDSP K_i Database									Eur J Pharmacol 304: 155-62 (1996) Article DOI: 10.1016/0014-2999(96)00088-x BindingDB Entry DOI: 10.7270/Q2HD7T6P
					More data for this Ligand-Target Pair
GABA A receptor alpha-6/beta-2/gamma-2 (Homo sapiens (Human))	BDBM26267 (RO-154513 \| Ro15-4513 \| [3H]Ro15-4513 \| ethyl 12-a...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	11.7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
CoCensys, Inc. Curated by PDSP K_i Database									Eur J Pharmacol 291: 319-25 (1995) Article DOI: 10.1016/0922-4106(95)90072-1 BindingDB Entry DOI: 10.7270/Q2JD4VB2
CoCensys, Inc. Curated by PDSP K_i Database					More data for this Ligand-Target Pair
GABA-A receptor; alpha-1/beta-2/gamma-2 (Homo sapiens (Human))	BDBM26267 (RO-154513 \| Ro15-4513 \| [3H]Ro15-4513 \| ethyl 12-a...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	15	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Upjohn Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]Flunitrazepam from GABA-A receptor alpha-1-beta-2-gamma-2 subunits expressed in Sf9 cells				J Med Chem 39: 158-75 (1996) Article DOI: 10.1021/jm940765f BindingDB Entry DOI: 10.7270/Q2PZ57WX
Upjohn Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
GABA receptor alpha-1/beta-3/gamma-2 subunit (Homo sapiens (Human))	BDBM26267 (RO-154513 \| Ro15-4513 \| [3H]Ro15-4513 \| ethyl 12-a...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	33	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Wisconsin-Milwaukee Curated by ChEMBL					Assay Description In vitro binding affinity for human GABA-A receptor alpha1-beta3-gamma2 subunits expressed in L(tk-) cell membranes				J Med Chem 46: 5567-70 (2003) Article DOI: 10.1021/jm034164c BindingDB Entry DOI: 10.7270/Q2R78DNC
University of Wisconsin-Milwaukee Curated by ChEMBL					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-1 (Homo sapiens (Human))	BDBM26267 (RO-154513 \| Ro15-4513 \| [3H]Ro15-4513 \| ethyl 12-a...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.10	n/a	n/a	n/a	n/a
University of Bern Curated by ChEMBL					Assay Description Activity at rat wild type GABAA alpha1beta2gamma2 receptor expressed in xenopus oocytes assessed as GABA-elicited response by two electrode voltage c...				J Biol Chem 282: 26316-25 (2007) Article DOI: 10.1074/jbc.M702153200 BindingDB Entry DOI: 10.7270/Q2PR7VR8
University of Bern Curated by ChEMBL					More data for this Ligand-Target Pair