BDBM26758 2-fluorophenyl N-[6-(2-methyl-4,5-diphenyl-1H-imidazol-1-yl)hexyl]carbamate::bisarylimidazole derivative, 17

SMILES: Cc1nc(c(-c2ccccc2)n1CCCCCCNC(=O)Oc1ccccc1F)-c1ccccc1

InChI Key: InChIKey=LHAHTHILLRCRBM-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 26758   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Fatty-acid amide hydrolase 1 (Homo sapiens (Human))	BDBM26758 (2-fluorophenyl N-[6-(2-methyl-4,5-diphenyl-1H-imid...) Show SMILES Cc1nc(c(-c2ccccc2)n1CCCCCCNC(=O)Oc1ccccc1F)-c1ccccc1 Show InChI InChI=1S/C29H30FN3O2/c1-22-32-27(23-14-6-4-7-15-23)28(24-16-8-5-9-17-24)33(22)21-13-3-2-12-20-31-29(34)35-26-19-11-10-18-25(26)30/h4-11,14-19H,2-3,12-13,20-21H2,1H3,(H,31,34)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	9.0	22
Bristol-Myers Squibb Company					Assay Description FAAH Inhibition Assay [3H]Ethanolamine produced from [3H]AEA hydrolysis was used to calculate FAAH activity and was measured by scintillation countin...				Bioorg Med Chem Lett 17: 3287-91 (2007) Article DOI: 10.1016/j.bmcl.2007.04.009 BindingDB Entry DOI: 10.7270/Q2R20ZPP
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 (Homo sapiens (Human))	BDBM26758 (2-fluorophenyl N-[6-(2-methyl-4,5-diphenyl-1H-imid...) Show SMILES Cc1nc(c(-c2ccccc2)n1CCCCCCNC(=O)Oc1ccccc1F)-c1ccccc1 Show InChI InChI=1S/C29H30FN3O2/c1-22-32-27(23-14-6-4-7-15-23)28(24-16-8-5-9-17-24)33(22)21-13-3-2-12-20-31-29(34)35-26-19-11-10-18-25(26)30/h4-11,14-19H,2-3,12-13,20-21H2,1H3,(H,31,34)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Inhibition of FAAH				J Med Chem 51: 7327-43 (2009) Article DOI: 10.1021/jm800311k BindingDB Entry DOI: 10.7270/Q2J67HT8
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 (Homo sapiens (Human))	BDBM26758 (2-fluorophenyl N-[6-(2-methyl-4,5-diphenyl-1H-imid...) Show SMILES Cc1nc(c(-c2ccccc2)n1CCCCCCNC(=O)Oc1ccccc1F)-c1ccccc1 Show InChI InChI=1S/C29H30FN3O2/c1-22-32-27(23-14-6-4-7-15-23)28(24-16-8-5-9-17-24)33(22)21-13-3-2-12-20-31-29(34)35-26-19-11-10-18-25(26)30/h4-11,14-19H,2-3,12-13,20-21H2,1H3,(H,31,34)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.70	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research& Development Curated by ChEMBL					Assay Description Inhibition of human FAAH expressed in human H4 cells				Bioorg Med Chem Lett 20: 1272-7 (2010) Article DOI: 10.1016/j.bmcl.2009.11.080 BindingDB Entry DOI: 10.7270/Q2H41RKR
					More data for this Ligand-Target Pair