BDBM272308 US10065950, Example 150

SMILES: COC[C@@H]1Cn2cc(-c3nnc(Cc4ccc(F)c(F)c4)s3)c(=O)c(O)c2C(=O)N1C(C)C

InChI Key: InChIKey=XUQNHDZKZZSQQV-ZDUSSCGKSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 272308   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
inhibitory activity (Human immunodeficiency virus type 1 group M subtyp...)	BDBM272308 (US10065950, Example 150) Show SMILES COC[C@@H]1Cn2cc(-c3nnc(Cc4ccc(F)c(F)c4)s3)c(=O)c(O)c2C(=O)N1C(C)C |r| Show InChI InChI=1S/C22H22F2N4O4S/c1-11(2)28-13(10-32-3)8-27-9-14(19(29)20(30)18(27)22(28)31)21-26-25-17(33-21)7-12-4-5-15(23)16(24)6-12/h4-6,9,11,13,30H,7-8,10H2,1-3H3/t13-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	6.10	n/a	n/a	n/a	n/a	n/a	25
Japan Tobacco Inc. US Patent					Assay Description The donor DNA was diluted with TE buffer to 20 nM, of which 50 μL was added to each well of streptavidin-coated black plate (manufactured by PIA...				US Patent US10065950 (2018) BindingDB Entry DOI: 10.7270/Q2RN39V2
					More data for this Ligand-Target Pair