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BDBM272942 (S)-1-(1-(2- aminobenzo[d]oxazol- 5-yl)-3-fluoro-7,8,9,10- tetrahydro-6-oxa-2,10a- diazacycloocta[cd]inden- 4-yl)pyrrolidine-2- carboxamide::US10065970, Example 247

SMILES: Nc1nc2cc(ccc2o1)-c1nc2c(F)c(cc3OCCCCn1c23)N1CCC[C@H]1C(F)=O

InChI Key:

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 272942   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform


(Homo sapiens (Human))
BDBM272942
PNG
((S)-1-(1-(2- aminobenzo[d]oxazol- 5-yl)-3-fluoro-7...)
Show SMILES Nc1nc2cc(ccc2o1)-c1nc2c(F)c(cc3OCCCCn1c23)N1CCC[C@H]1C(F)=O |r|
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
0.0240n/an/an/an/an/an/an/an/a



Genentech, Inc.

US Patent




US Patent US10065970 (2018)


BindingDB Entry DOI: 10.7270/Q27P91FB
More data for this
Ligand-Target Pair