BDBM27419 2-[2-(propylamino)pyrimidin-4-yl]-1H,4H,5H,6H,7H-pyrrolo[3,2-c]pyridin-4-one::pyrrolopyridinone scaffold, 41

SMILES: CCCNc1nccc(n1)-c1cc2c(CCNC2=O)[nH]1

InChI Key: InChIKey=DIDPHYKBWXCRNK-UHFFFAOYSA-N

Data: 1 IC50

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Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 27419   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cdc7 Kinase (Homo sapiens (Human))	BDBM27419 (2-[2-(propylamino)pyrimidin-4-yl]-1H,4H,5H,6H,7H-p...) Show SMILES CCCNc1nccc(n1)-c1cc2c(CCNC2=O)[nH]1 Show InChI InChI=1S/C14H17N5O/c1-2-5-16-14-17-7-4-11(19-14)12-8-9-10(18-12)3-6-15-13(9)20/h4,7-8,18H,2-3,5-6H2,1H3,(H,15,20)(H,16,17,19)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	259	n/a	n/a	n/a	n/a	n/a	n/a
Nerviano Medical Sciences Srl					Assay Description The potency of the compound toward kinase activity was determined using a Dowex resin-based assay. The substrate was phosphorylated by kinase in the ...				J Med Chem 51: 487-501 (2008) Article DOI: 10.1021/jm700956r BindingDB Entry DOI: 10.7270/Q247485B
					More data for this Ligand-Target Pair