BDBM27662 4-[(3-{[4-(2-phenoxypropanoyl)piperazin-1-yl]carbonyl}phenyl)methyl]-1,2-dihydrophthalazin-1-one::phthalazinone, 4

SMILES: CC(Oc1ccccc1)C(=O)N1CCN(CC1)C(=O)c1cccc(Cc2n[nH]c(=O)c3ccccc23)c1

InChI Key: InChIKey=SPXYGEVHERLLRQ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 27662   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Poly [ADP-ribose] polymerase 1 (Homo sapiens (Human))	BDBM27662 (4-[(3-{[4-(2-phenoxypropanoyl)piperazin-1-yl]carbo...) Show SMILES CC(Oc1ccccc1)C(=O)N1CCN(CC1)C(=O)c1cccc(Cc2n[nH]c(=O)c3ccccc23)c1 Show InChI InChI=1S/C29H28N4O4/c1-20(37-23-10-3-2-4-11-23)28(35)32-14-16-33(17-15-32)29(36)22-9-7-8-21(18-22)19-26-24-12-5-6-13-25(24)27(34)31-30-26/h2-13,18,20H,14-17,19H2,1H3,(H,31,34)	PDB MMDB UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	7.4	22
KuDOS Pharmaceuticals Ltd					Assay Description A FlashPlate scintillation proximity assay has been developed to identify inhibitors of PARP-1. The mechanism of action of the assay requires the bin...				Bioorg Med Chem Lett 18: 3942-5 (2008) Article DOI: 10.1016/j.bmcl.2008.06.025 BindingDB Entry DOI: 10.7270/Q2FF3QPX
					More data for this Ligand-Target Pair