BDBM27665 2-({3-[(4-cyclopentanecarbonylpiperazin-1-yl)carbonyl]phenyl}methoxy)benzamide::substituted 2-benzyloxybenzamide, 7

SMILES: NC(=O)c1ccccc1OCc1cccc(c1)C(=O)N1CCN(CC1)C(=O)C1CCCC1

InChI Key: InChIKey=AKPOXCRWIFVINR-UHFFFAOYSA-N

Data: 1 IC50

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Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 27665   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Poly [ADP-ribose] polymerase 1 (Homo sapiens (Human))	BDBM27665 (2-({3-[(4-cyclopentanecarbonylpiperazin-1-yl)carbo...) Show SMILES NC(=O)c1ccccc1OCc1cccc(c1)C(=O)N1CCN(CC1)C(=O)C1CCCC1 Show InChI InChI=1S/C25H29N3O4/c26-23(29)21-10-3-4-11-22(21)32-17-18-6-5-9-20(16-18)25(31)28-14-12-27(13-15-28)24(30)19-7-1-2-8-19/h3-6,9-11,16,19H,1-2,7-8,12-15,17H2,(H2,26,29)	PDB MMDB UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	188	n/a	n/a	n/a	n/a	7.4	22
KuDOS Pharmaceuticals Ltd					Assay Description A FlashPlate scintillation proximity assay has been developed to identify inhibitors of PARP-1. The mechanism of action of the assay requires the bin...				Bioorg Med Chem Lett 18: 3942-5 (2008) Article DOI: 10.1016/j.bmcl.2008.06.025 BindingDB Entry DOI: 10.7270/Q2FF3QPX
					More data for this Ligand-Target Pair