BDBM27669 2-{2-[3-(piperazin-1-ylcarbonyl)phenyl]ethoxy}benzamide::substituted 2-phenethyloxybenzamide, 11

SMILES: NC(=O)c1ccccc1OCCc1cccc(c1)C(=O)N1CCNCC1

InChI Key: InChIKey=JLQAPOMVNMZQSX-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 27669   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Poly [ADP-ribose] polymerase 1 (Homo sapiens (Human))	BDBM27669 (2-{2-[3-(piperazin-1-ylcarbonyl)phenyl]ethoxy}benz...) Show SMILES NC(=O)c1ccccc1OCCc1cccc(c1)C(=O)N1CCNCC1 Show InChI InChI=1S/C20H23N3O3/c21-19(24)17-6-1-2-7-18(17)26-13-8-15-4-3-5-16(14-15)20(25)23-11-9-22-10-12-23/h1-7,14,22H,8-13H2,(H2,21,24)	PDB MMDB UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	970	n/a	n/a	n/a	n/a	7.4	22
KuDOS Pharmaceuticals Ltd					Assay Description A FlashPlate scintillation proximity assay has been developed to identify inhibitors of PARP-1. The mechanism of action of the assay requires the bin...				Bioorg Med Chem Lett 18: 3942-5 (2008) Article DOI: 10.1016/j.bmcl.2008.06.025 BindingDB Entry DOI: 10.7270/Q2FF3QPX
					More data for this Ligand-Target Pair