BDBM27672 2-(2-{3-[(4-cyclopentanecarbonylpiperazin-1-yl)carbonyl]-4-fluorophenyl}ethoxy)benzamide::substituted 2-phenethyloxybenzamide, 14

SMILES: NC(=O)c1ccccc1OCCc1ccc(F)c(c1)C(=O)N1CCN(CC1)C(=O)C1CCCC1

InChI Key: InChIKey=MGRXLBMAFBOFSC-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 27672   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Poly [ADP-ribose] polymerase 1 (Homo sapiens (Human))	BDBM27672 (2-(2-{3-[(4-cyclopentanecarbonylpiperazin-1-yl)car...) Show SMILES NC(=O)c1ccccc1OCCc1ccc(F)c(c1)C(=O)N1CCN(CC1)C(=O)C1CCCC1 Show InChI InChI=1S/C26H30FN3O4/c27-22-10-9-18(11-16-34-23-8-4-3-7-20(23)24(28)31)17-21(22)26(33)30-14-12-29(13-15-30)25(32)19-5-1-2-6-19/h3-4,7-10,17,19H,1-2,5-6,11-16H2,(H2,28,31)	PDB MMDB UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	103	n/a	n/a	n/a	n/a	7.4	22
KuDOS Pharmaceuticals Ltd					Assay Description A FlashPlate scintillation proximity assay has been developed to identify inhibitors of PARP-1. The mechanism of action of the assay requires the bin...				Bioorg Med Chem Lett 18: 3942-5 (2008) Article DOI: 10.1016/j.bmcl.2008.06.025 BindingDB Entry DOI: 10.7270/Q2FF3QPX
					More data for this Ligand-Target Pair