null

SMILES: COc1cc(C)c(CCCN(C)C)cc1Nc1nc(Nc2cccc(F)c2C(N)=O)c2cc[nH]c2n1

InChI Key: InChIKey=MYPQGCUDQYBJLG-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 27789   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 8 (Homo sapiens (Human))	BDBM27789 (2-{[2-({5-[3-(dimethylamino)propyl]-2-methoxy-4-me...) Show SMILES COc1cc(C)c(CCCN(C)C)cc1Nc1nc(Nc2cccc(F)c2C(N)=O)c2cc[nH]c2n1 Show InChI InChI=1S/C26H30FN7O2/c1-15-13-21(36-4)20(14-16(15)7-6-12-34(2)3)31-26-32-24-17(10-11-29-24)25(33-26)30-19-9-5-8-18(27)22(19)23(28)35/h5,8-11,13-14H,6-7,12H2,1-4H3,(H2,28,35)(H3,29,30,31,32,33)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	501	n/a	n/a	n/a	n/a	n/a	n/a
GSK					Assay Description Assays are performed in 384-well microtiter plates in reaction buffer containing substrate GST-biotin-C-JUN, ATP, and purified activated JNK1alpha1 i...				Bioorg Med Chem Lett 19: 360-4 (2009) Article DOI: 10.1016/j.bmcl.2008.11.077 BindingDB Entry DOI: 10.7270/Q2NZ85ZT
					More data for this Ligand-Target Pair
Insulin-like growth factor 1 receptor (Homo sapiens (Human))	BDBM27789 (2-{[2-({5-[3-(dimethylamino)propyl]-2-methoxy-4-me...) Show SMILES COc1cc(C)c(CCCN(C)C)cc1Nc1nc(Nc2cccc(F)c2C(N)=O)c2cc[nH]c2n1 Show InChI InChI=1S/C26H30FN7O2/c1-15-13-21(36-4)20(14-16(15)7-6-12-34(2)3)31-26-32-24-17(10-11-29-24)25(33-26)30-19-9-5-8-18(27)22(19)23(28)35/h5,8-11,13-14H,6-7,12H2,1-4H3,(H2,28,35)(H3,29,30,31,32,33)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	7.5	22
GSK					Assay Description Assays are performed in 384-well microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified activated GST-IGF-1R in th...				Bioorg Med Chem Lett 19: 360-4 (2009) Article DOI: 10.1016/j.bmcl.2008.11.077 BindingDB Entry DOI: 10.7270/Q2NZ85ZT
					More data for this Ligand-Target Pair