BDBM28036 N-(4-phenylphenyl)-2-(1H-1,2,3,4-tetrazol-5-yl)thieno[2,3-c]pyridin-4-amine::thieno[2,3-c]pyridine, 3c

SMILES: N(c1ccc(cc1)-c1ccccc1)c1cncc2sc(cc12)-c1nnn[nH]1

InChI Key: InChIKey=TUPRKLVIDDKQDQ-UHFFFAOYSA-N

Data: 1 IC50

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Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 28036   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase kinase kinase 8 (Homo sapiens (Human))	BDBM28036 (N-(4-phenylphenyl)-2-(1H-1,2,3,4-tetrazol-5-yl)thi...) Show SMILES N(c1ccc(cc1)-c1ccccc1)c1cncc2sc(cc12)-c1nnn[nH]1 Show InChI InChI=1S/C20H14N6S/c1-2-4-13(5-3-1)14-6-8-15(9-7-14)22-17-11-21-12-19-16(17)10-18(27-19)20-23-25-26-24-20/h1-12,22H,(H,23,24,25,26)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	210	n/a	n/a	n/a	n/a	7.5	22
Abbott Laboratories					Assay Description The COT direct HTRF assay was carried out using biotin-MEK1 as a substrate. The reaction was carried out in black 96 half-well plates. At designated...				Bioorg Med Chem Lett 19: 1722-5 (2009) Article DOI: 10.1016/j.bmcl.2009.01.088 BindingDB Entry DOI: 10.7270/Q2VH5M4P
					More data for this Ligand-Target Pair