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SMILES: O[C@H](CNC(=O)c1cccc(NC2CCOCC2)c1)CN1Cc2ccccc2C1

InChI Key: InChIKey=ISDGHQQLLYNJMG-JOCHJYFZSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 297745   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein arginine N-methyltransferase 5 (Homo sapiens (Human))	BDBM297745 (US10118918, Compound 24 | US9732072, Compound 24) Show SMILES O[C@H](CNC(=O)c1cccc(NC2CCOCC2)c1)CN1Cc2ccccc2C1 |r| Show InChI InChI=1S/C23H29N3O3/c27-22(16-26-14-18-4-1-2-5-19(18)15-26)13-24-23(28)17-6-3-7-21(12-17)25-20-8-10-29-11-9-20/h1-7,12,20,22,25,27H,8-11,13-16H2,(H,24,28)/t22-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Epizyme, Inc. US Patent					Assay Description General Materials.S-adenosylmethionine (SAM), S-adenosylhomocysteine (SAH), bicine, KCl, Tween20, dimethylsulfoxide (DMSO), bovine skin gelatin (BSG)...				US Patent US9732072 (2017) BindingDB Entry DOI: 10.7270/Q2FF3VGW
					More data for this Ligand-Target Pair
Protein arginine N-methyltransferase 5 (Homo sapiens (Human))	BDBM297745 (US10118918, Compound 24 | US9732072, Compound 24) Show SMILES O[C@H](CNC(=O)c1cccc(NC2CCOCC2)c1)CN1Cc2ccccc2C1 |r| Show InChI InChI=1S/C23H29N3O3/c27-22(16-26-14-18-4-1-2-5-19(18)15-26)13-24-23(28)17-6-3-7-21(12-17)25-20-8-10-29-11-9-20/h1-7,12,20,22,25,27H,8-11,13-16H2,(H,24,28)/t22-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Epizyme, Inc. US Patent					Assay Description The assays were all performed in a buffer consisting of 20 mM Bicine (pH=7.6), 1 mM TCEP, 0.005% BSG, and 0.002% Tween20, prepared on the day of use....				US Patent US10118918 (2018) BindingDB Entry DOI: 10.7270/Q2ZS2ZK6
					More data for this Ligand-Target Pair