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SMILES: O[C@@H](CNC(=O)c1cc(NC2COC2)nc(n1)N1CCOCC1)CN1Cc2ccccc2C1

InChI Key: InChIKey=GBMPFWQSSHCLII-IBGZPJMESA-N

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 297756   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Protein arginine N-methyltransferase 5


(Homo sapiens (Human))		BDBM297756
PNG
(US10118918, Compound 38)
Show SMILES O[C@@H](CNC(=O)c1cc(NC2COC2)nc(n1)N1CCOCC1)CN1Cc2ccccc2C1 |r|
Show InChI InChI=1S/C23H30N6O4/c30-19(13-28-11-16-3-1-2-4-17(16)12-28)10-24-22(31)20-9-21(25-18-14-33-15-18)27-23(26-20)29-5-7-32-8-6-29/h1-4,9,18-19,30H,5-8,10-15H2,(H,24,31)(H,25,26,27)/t19-/m0/s1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a<100n/an/an/an/an/an/a



Epizyme, Inc.

US Patent


Assay Description
The assays were all performed in a buffer consisting of 20 mM Bicine (pH=7.6), 1 mM TCEP, 0.005% BSG, and 0.002% Tween20, prepared on the day of use....

US Patent US10118918 (2018)


BindingDB Entry DOI: 10.7270/Q2ZS2ZK6
More data for this
Ligand-Target Pair