BDBM309313 (3R,4S)-4-(4-fluorophenyl)-N-[4-fluoro-3-(trifluoromethoxy)phenyl]-1-[(1-methyl-1H-1,2,3-triazol-4-yl)sulfonyl]pyrrolidin-3-amine::US9656955, Example 838

SMILES: Cn1cc(nn1)S(=O)(=O)N1C[C@H](Nc2ccc(F)c(OC(F)(F)F)c2)[C@H](C1)c1ccc(F)cc1

InChI Key: InChIKey=KWVKYMHGIFTHCL-WBVHZDCISA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 309313   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase (Homo sapiens (Human))	BDBM309313 ((3R,4S)-4-(4-fluorophenyl)-N-[4-fluoro-3-(trifluor...) Show SMILES Cn1cc(nn1)S(=O)(=O)N1C[C@H](Nc2ccc(F)c(OC(F)(F)F)c2)[C@H](C1)c1ccc(F)cc1 Show InChI InChI=1S/C20H18F5N5O3S/c1-29-11-19(27-28-29)34(31,32)30-9-15(12-2-4-13(21)5-3-12)17(10-30)26-14-6-7-16(22)18(8-14)33-20(23,24)25/h2-8,11,15,17,26H,9-10H2,1H3/t15-,17+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Inc.; AbbVie Deutschland GmbH & Co. KG US Patent					Assay Description Radioligand binding assays using recombinant CHO cell membranes expressing human GlyT1: Radioligand binding to human GlyT1c transporter-expressing me...				US Patent US9656955 (2017) BindingDB Entry DOI: 10.7270/Q2Z60R48
					More data for this Ligand-Target Pair