BDBM312453 2-[3-(3-Cyclopropyl-[1,2,4]thiadiazol-5-yl)-6,6-difluoro-4,5,6,7-tetrahydro-benzo[b]thiophen-2-ylcarbamoyl]-cyclohex-1-enecarboxylic acid::US9604977, Example 199

SMILES: OC(=O)C1=C(CCCC1)C(=O)Nc1sc2CC(F)(F)CCc2c1-c1nc(ns1)C1CC1

InChI Key: InChIKey=LWRZNUDGZAKDPB-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 312453   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Fatty acid-binding protein 5 (FABP5) (Homo sapiens (Human))	BDBM312453 (2-[3-(3-Cyclopropyl-[1,2,4]thiadiazol-5-yl)-6,6-di...) Show SMILES OC(=O)C1=C(CCCC1)C(=O)Nc1sc2CC(F)(F)CCc2c1-c1nc(ns1)C1CC1 |t:3| Show InChI InChI=1S/C21H21F2N3O3S2/c22-21(23)8-7-13-14(9-21)30-18(15(13)19-24-16(26-31-19)10-5-6-10)25-17(27)11-3-1-2-4-12(11)20(28)29/h10H,1-9H2,(H,25,27)(H,28,29)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	33	n/a	n/a	n/a	n/a	n/a	n/a
Hoffman-La Roche Inc. US Patent					Assay Description Compounds were profiled for activity against human FABP4 (huFABP4) and/or human FABP5 (huFABP5) in Terbium (Tb) time resolved-fluorescence energy tra...				US Patent US9604977 (2017) BindingDB Entry DOI: 10.7270/Q2FX7CJB
					More data for this Ligand-Target Pair
Fatty acid-binding protein 4 (FABP4) (Homo sapiens (Human))	BDBM312453 (2-[3-(3-Cyclopropyl-[1,2,4]thiadiazol-5-yl)-6,6-di...) Show SMILES OC(=O)C1=C(CCCC1)C(=O)Nc1sc2CC(F)(F)CCc2c1-c1nc(ns1)C1CC1 |t:3| Show InChI InChI=1S/C21H21F2N3O3S2/c22-21(23)8-7-13-14(9-21)30-18(15(13)19-24-16(26-31-19)10-5-6-10)25-17(27)11-3-1-2-4-12(11)20(28)29/h10H,1-9H2,(H,25,27)(H,28,29)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Hoffman-La Roche Inc. US Patent					Assay Description Compounds were profiled for activity against human FABP4 (huFABP4) and/or human FABP5 (huFABP5) in Terbium (Tb) time resolved-fluorescence energy tra...				US Patent US9604977 (2017) BindingDB Entry DOI: 10.7270/Q2FX7CJB
					More data for this Ligand-Target Pair