BDBM312471 2-[5-(3-Cyclopropyl-[1,2,4]oxadiazol-5-yl)-3,4-dihydro-2H-thieno[2,3-b]pyran-6-ylcarbamoyl]-cyclopent-1-enecarboxylic acid::US9604977, Example 217

SMILES: OC(=O)C1=C(CCC1)C(=O)Nc1sc2OCCCc2c1-c1nc(no1)C1CC1

InChI Key: InChIKey=RTVNMPQRCAODMR-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 312471   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Fatty acid-binding protein 5 (FABP5) (Homo sapiens (Human))	BDBM312471 (2-[5-(3-Cyclopropyl-[1,2,4]oxadiazol-5-yl)-3,4-dih...) Show SMILES OC(=O)C1=C(CCC1)C(=O)Nc1sc2OCCCc2c1-c1nc(no1)C1CC1 |t:3| Show InChI InChI=1S/C19H19N3O5S/c23-15(10-3-1-4-11(10)18(24)25)21-17-13(12-5-2-8-26-19(12)28-17)16-20-14(22-27-16)9-6-7-9/h9H,1-8H2,(H,21,23)(H,24,25)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	34	n/a	n/a	n/a	n/a	n/a	n/a
Hoffman-La Roche Inc. US Patent					Assay Description Compounds were profiled for activity against human FABP4 (huFABP4) and/or human FABP5 (huFABP5) in Terbium (Tb) time resolved-fluorescence energy tra...				US Patent US9604977 (2017) BindingDB Entry DOI: 10.7270/Q2FX7CJB
					More data for this Ligand-Target Pair
Fatty acid-binding protein 4 (FABP4) (Homo sapiens (Human))	BDBM312471 (2-[5-(3-Cyclopropyl-[1,2,4]oxadiazol-5-yl)-3,4-dih...) Show SMILES OC(=O)C1=C(CCC1)C(=O)Nc1sc2OCCCc2c1-c1nc(no1)C1CC1 |t:3| Show InChI InChI=1S/C19H19N3O5S/c23-15(10-3-1-4-11(10)18(24)25)21-17-13(12-5-2-8-26-19(12)28-17)16-20-14(22-27-16)9-6-7-9/h9H,1-8H2,(H,21,23)(H,24,25)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
Hoffman-La Roche Inc. US Patent					Assay Description Compounds were profiled for activity against human FABP4 (huFABP4) and/or human FABP5 (huFABP5) in Terbium (Tb) time resolved-fluorescence energy tra...				US Patent US9604977 (2017) BindingDB Entry DOI: 10.7270/Q2FX7CJB
					More data for this Ligand-Target Pair