BindingDB logo
myBDB logout

null

SMILES: Clc1ccc(CNc2nc3n(ncc3c(=O)[nH]2)C2CCCC2)cc1

InChI Key: InChIKey=KBXZZLXKUOADBU-UHFFFAOYSA-N

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 317074   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A


(Homo sapiens (Human))		BDBM317074
PNG
(US9617269, Compound WYQ-25)
Show SMILES Clc1ccc(CNc2nc3n(ncc3c(=O)[nH]2)C2CCCC2)cc1
Show InChI InChI=1S/C17H18ClN5O/c18-12-7-5-11(6-8-12)9-19-17-21-15-14(16(24)22-17)10-20-23(15)13-3-1-2-4-13/h5-8,10,13H,1-4,9H2,(H2,19,21,22,24)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 4n/an/an/an/an/an/a



Sun Yat-Sen University; University of North Carolina at Chapel Hill

US Patent


Assay Description
Inhibition activities of all the N-substituted pyrazolo [3,4-d] pyrimidine ketone compounds according to the present invention to the phosphodiestera...

US Patent US9617269 (2017)


BindingDB Entry DOI: 10.7270/Q2RX9F4B
More data for this
Ligand-Target Pair