Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A' and Ligand = 'BDBM317074'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A (Homo sapiens (Human))	BDBM317074 (US9617269, Compound WYQ-25) Show SMILES Clc1ccc(CNc2nc3n(ncc3c(=O)[nH]2)C2CCCC2)cc1 Show InChI InChI=1S/C17H18ClN5O/c18-12-7-5-11(6-8-12)9-19-17-21-15-14(16(24)22-17)10-20-23(15)13-3-1-2-4-13/h5-8,10,13H,1-4,9H2,(H2,19,21,22,24)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Sun Yat-Sen University; University of North Carolina at Chapel Hill US Patent					Assay Description Inhibition activities of all the N-substituted pyrazolo [3,4-d] pyrimidine ketone compounds according to the present invention to the phosphodiestera...				US Patent US9617269 (2017) BindingDB Entry DOI: 10.7270/Q2RX9F4B
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