BDBM318968 US10173991, Example 9::benzyl N-{4-[2- ({[(cyclopropyl- carbamoyl) methyl] carbamoyl} (3,3,3-trifluoro- propanesulfonyl) methyl)-6-fluoro- 1,3-benzothiazol- 5-yl]phenyl} carbamate

SMILES: Fc1cc2sc(nc2cc1-c1ccc(NC(=O)OCc2ccccc2)cc1)C(C(=O)NCC(=O)NC1CC1)S(=O)(=O)CCC(F)(F)F

InChI Key: InChIKey=IIOZHYQWCQCNIP-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 318968   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Endothelial lipase (Homo sapiens (Human))	BDBM318968 (US10173991, Example 9 | benzyl N-{4-[2- ({[(cyclop...) Show SMILES Fc1cc2sc(nc2cc1-c1ccc(NC(=O)OCc2ccccc2)cc1)C(C(=O)NCC(=O)NC1CC1)S(=O)(=O)CCC(F)(F)F Show InChI InChI=1S/C31H28F4N4O6S2/c32-23-15-25-24(14-22(23)19-6-8-21(9-7-19)38-30(42)45-17-18-4-2-1-3-5-18)39-29(46-25)27(47(43,44)13-12-31(33,34)35)28(41)36-16-26(40)37-20-10-11-20/h1-9,14-15,20,27H,10-13,16-17H2,(H,36,41)(H,37,40)(H,38,42)	KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description Endothelial lipase (EL) and hepatic lipase (HL) activities were measured using a fluorescent substrate, A10070, (Invitrogen, CA) doped into an artifi...				US Patent US10173991 (2019) BindingDB Entry DOI: 10.7270/Q2N018M8
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