BDBM31960 carbohydrazide derivative, 5c

SMILES: Oc1c(Br)cc(C=NNC(=O)c2cc(cc(c2)C(F)(F)F)C(F)(F)F)c(O)c1Br

InChI Key: InChIKey=BHPSZHFOPFVKLN-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 31960   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
beta-Hydroxyacyl-Acyl Carrier Protein Dehydratase (FabZ) (Helicobacter pylori (Campylobacter pylori))	BDBM31960 (carbohydrazide derivative, 5c) Show SMILES Oc1c(Br)cc(C=NNC(=O)c2cc(cc(c2)C(F)(F)F)C(F)(F)F)c(O)c1Br |w:6.5| Show InChI InChI=1S/C16H8Br2F6N2O3/c17-10-3-7(12(27)11(18)13(10)28)5-25-26-14(29)6-1-8(15(19,20)21)4-9(2-6)16(22,23)24/h1-5,27-28H,(H,26,29)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.13E+3	n/a	n/a	n/a	n/a	n/a	n/a
Shanghai Institute of Materia Medica					Assay Description The enzymatic inhibition assay of HpFabZ was monitored by the spectrophotometric method. The activity of HpFabZ was measured by detection of the decr...				J Med Chem 52: 2465-81 (2009) Article DOI: 10.1021/jm8015602 BindingDB Entry DOI: 10.7270/Q2ZK5F1W
					More data for this Ligand-Target Pair