BDBM319789 US10174015, Compound 2

SMILES: O=C(CCCCCc1ccccc1)N1CCOC1=O

InChI Key: InChIKey=OXZXDYAGMMUIBN-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 319789   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
N-acylethanolamine-hydrolyzing acid amidase (Homo sapiens (Human))	BDBM319789 (US10174015, Compound 2) Show SMILES O=C(CCCCCc1ccccc1)N1CCOC1=O Show InChI InChI=1S/C15H19NO3/c17-14(16-11-12-19-15(16)18)10-6-2-5-9-13-7-3-1-4-8-13/h1,3-4,7-8H,2,5-6,9-12H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	210	n/a	n/a	n/a	n/a	n/a	n/a
Xiamen University US Patent					Assay Description In the Experimental example, endocannabinoid hydrolases used were Fatty Acid Amide Hydrolase (FAAH) and N-acylethanolamide hydrolyzing acid amidase (...				US Patent US10174015 (2019) BindingDB Entry DOI: 10.7270/Q2M047JS
					More data for this Ligand-Target Pair
Acid ceramidase (AC) (Rattus norvegicus (Rat))	BDBM319789 (US10174015, Compound 2) Show SMILES O=C(CCCCCc1ccccc1)N1CCOC1=O Show InChI InChI=1S/C15H19NO3/c17-14(16-11-12-19-15(16)18)10-6-2-5-9-13-7-3-1-4-8-13/h1,3-4,7-8H,2,5-6,9-12H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	270	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of rat acid ceramidase expressed in HEK293 cells using N-lauroylceramide as substrate after 30 mins by LC-MS analysis				Eur J Med Chem 139: 214-221 (2017) Article DOI: 10.1016/j.ejmech.2017.08.004 BindingDB Entry DOI: 10.7270/Q2FR007C
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 (Homo sapiens (Human))	BDBM319789 (US10174015, Compound 2) Show SMILES O=C(CCCCCc1ccccc1)N1CCOC1=O Show InChI InChI=1S/C15H19NO3/c17-14(16-11-12-19-15(16)18)10-6-2-5-9-13-7-3-1-4-8-13/h1,3-4,7-8H,2,5-6,9-12H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Xiamen University US Patent					Assay Description In the Experimental example, endocannabinoid hydrolases used were Fatty Acid Amide Hydrolase (FAAH) and N-acylethanolamide hydrolyzing acid amidase (...				US Patent US10174015 (2019) BindingDB Entry DOI: 10.7270/Q2M047JS
					More data for this Ligand-Target Pair