BDBM3407 2-Butanol deriv. 15::N-tert-butyl-4-{4-[1-(tert-butylcarbamoyl)naphthalen-2-yl]-2-hydroxybutyl}-1-(propan-2-yl)-1,2,5,6-tetrahydropyridine-3-carboxamide

SMILES: CC(C)N1CCC(CC(O)CCc2ccc3ccccc3c2C(=O)NC(C)(C)C)=C(C1)C(=O)NC(C)(C)C

InChI Key: InChIKey=LQZRQBAANWHPBV-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 3407   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
HIV-1 Protease (Human immunodeficiency virus type 1)	BDBM3407 (2-Butanol deriv. 15 | N-tert-butyl-4-{4-[1-(tert-b...) Show SMILES CC(C)N1CCC(CC(O)CCc2ccc3ccccc3c2C(=O)NC(C)(C)C)=C(C1)C(=O)NC(C)(C)C |c:30| Show InChI InChI=1S/C32H47N3O3/c1-21(2)35-18-17-24(27(20-35)29(37)33-31(3,4)5)19-25(36)16-15-23-14-13-22-11-9-10-12-26(22)28(23)30(38)34-32(6,7)8/h9-14,21,25,36H,15-20H2,1-8H3,(H,33,37)(H,34,38)	PDB MMDB B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	7.00E+4	n/a	n/a	n/a	n/a	5.6	37
Agouron Pharmaceuticals, Inc.					Assay Description Protease activity was measured by continuous chromogenic assay. The chromogenic peptide His-Lys-Ala-Arg-Val-Leu- (p-NO2-Phe)-Glu-Ala-Nleu-Ser (Bache...				J Med Chem 39: 2781-94 (1996) Article DOI: 10.1021/jm960093o BindingDB Entry DOI: 10.7270/Q2K072F6
					More data for this Ligand-Target Pair