null

SMILES: COc1ccc(cc1)-c1[nH]c(nc1C)C1CCN(CC1)c1ncnc2[nH]c(cc12)-c1ccc(cc1)C#N

InChI Key: InChIKey=GDVGXWHYTKNEQZ-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 342176   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mast/stem cell growth factor receptor Kit [D816V] (Homo sapiens (Human))	BDBM342176 (4-[4-[4-[5-(4-methoxyphenyl)-4-methyl- 1H-imidazol...) Show SMILES COc1ccc(cc1)-c1[nH]c(nc1C)C1CCN(CC1)c1ncnc2[nH]c(cc12)-c1ccc(cc1)C#N Show InChI InChI=1S/C29H27N7O/c1-18-26(21-7-9-23(37-2)10-8-21)35-27(33-18)22-11-13-36(14-12-22)29-24-15-25(34-28(24)31-17-32-29)20-5-3-19(16-30)4-6-20/h3-10,15,17,22H,11-14H2,1-2H3,(H,33,35)(H,31,32,34)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	500	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Plexxikon Inc. US Patent					Assay Description The c-kit mutant D816V (or kinase domain thereof) is an active kinase in AlphaScreen. IC50 values are determined with respect to inhibition of c-Kit ...				US Patent US9771369 (2017) BindingDB Entry DOI: 10.7270/Q24J0H7Q
					More data for this Ligand-Target Pair
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human))	BDBM342176 (4-[4-[4-[5-(4-methoxyphenyl)-4-methyl- 1H-imidazol...) Show SMILES COc1ccc(cc1)-c1[nH]c(nc1C)C1CCN(CC1)c1ncnc2[nH]c(cc12)-c1ccc(cc1)C#N Show InChI InChI=1S/C29H27N7O/c1-18-26(21-7-9-23(37-2)10-8-21)35-27(33-18)22-11-13-36(14-12-22)29-24-15-25(34-28(24)31-17-32-29)20-5-3-19(16-30)4-6-20/h3-10,15,17,22H,11-14H2,1-2H3,(H,33,35)(H,31,32,34)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	500	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Plexxikon Inc. US Patent					Assay Description Assays for biochemical cell-based activity of c-kit kinase are known in the art, for example, as described in U.S. Pat. Nos. 7,498,342 and 7,846,941,...				US Patent US9771369 (2017) BindingDB Entry DOI: 10.7270/Q24J0H7Q
					More data for this Ligand-Target Pair