null

SMILES: COc1ccc(cc1)-c1[nH]c(nc1C)C1CCN(CC1)c1ncnc2[nH]c(cc12)-c1ccnc(OC)c1

InChI Key: InChIKey=NDJACHUXQUQBDR-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 342178   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mast/stem cell growth factor receptor Kit [D816V] (Homo sapiens (Human))	BDBM342178 (4-[4-[5-(4-methoxyphenyl)-4-methyl- 1H-imidazol-2-...) Show SMILES COc1ccc(cc1)-c1[nH]c(nc1C)C1CCN(CC1)c1ncnc2[nH]c(cc12)-c1ccnc(OC)c1 Show InChI InChI=1S/C28H29N7O2/c1-17-25(18-4-6-21(36-2)7-5-18)34-26(32-17)19-9-12-35(13-10-19)28-22-15-23(33-27(22)30-16-31-28)20-8-11-29-24(14-20)37-3/h4-8,11,14-16,19H,9-10,12-13H2,1-3H3,(H,32,34)(H,30,31,33)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	500	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Plexxikon Inc. US Patent					Assay Description The c-kit mutant D816V (or kinase domain thereof) is an active kinase in AlphaScreen. IC50 values are determined with respect to inhibition of c-Kit ...				US Patent US9771369 (2017) BindingDB Entry DOI: 10.7270/Q24J0H7Q
					More data for this Ligand-Target Pair
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human))	BDBM342178 (4-[4-[5-(4-methoxyphenyl)-4-methyl- 1H-imidazol-2-...) Show SMILES COc1ccc(cc1)-c1[nH]c(nc1C)C1CCN(CC1)c1ncnc2[nH]c(cc12)-c1ccnc(OC)c1 Show InChI InChI=1S/C28H29N7O2/c1-17-25(18-4-6-21(36-2)7-5-18)34-26(32-17)19-9-12-35(13-10-19)28-22-15-23(33-27(22)30-16-31-28)20-8-11-29-24(14-20)37-3/h4-8,11,14-16,19H,9-10,12-13H2,1-3H3,(H,32,34)(H,30,31,33)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	500	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Plexxikon Inc. US Patent					Assay Description Assays for biochemical cell-based activity of c-kit kinase are known in the art, for example, as described in U.S. Pat. Nos. 7,498,342 and 7,846,941,...				US Patent US9771369 (2017) BindingDB Entry DOI: 10.7270/Q24J0H7Q
					More data for this Ligand-Target Pair