null
SMILES: Cc1cccc(c1)-c1cc(COC(C)(C)C(O)=O)nn1Cc1ccccc1Cl
InChI Key: InChIKey=GKQYGOVLFGQJQP-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Monocarboxylate transporter 4 (Homo sapiens (Human)) | BDBM345265 (2-[[1-[(2-Chlorophenyl)methyl]-5-(m- tolyl)pyrazo...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 45 | n/a | n/a | n/a | n/a | n/a | n/a |
Vettore, LLC US Patent | Assay Description MCT4 may be stably expressed in MDA-MB-453 breast cancer cells that do not express native MCT1 or MCT4. MCT4 activity may be assessed by monitoring t... | US Patent US10202350 (2019) BindingDB Entry DOI: 10.7270/Q20K2BPB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Monocarboxylate transporter 4 (Homo sapiens (Human)) | BDBM345265 (2-[[1-[(2-Chlorophenyl)methyl]-5-(m- tolyl)pyrazo...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 25 | n/a | n/a | n/a | n/a | n/a | n/a |
Vettore, LLC US Patent | Assay Description NCI-H358 lung adenocarcinoma cells may be used to measure MCT4 activity in cells with high native levels of MCT4 and low levels of MCT1 and are known... | US Patent US10202350 (2019) BindingDB Entry DOI: 10.7270/Q20K2BPB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Malignant T-cell-amplified sequence 1 (Homo sapiens (human)) | BDBM345265 (2-[[1-[(2-Chlorophenyl)methyl]-5-(m- tolyl)pyrazo...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 2.90E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Vettore, LLC US Patent | Assay Description MCT1 activity may be measured using BT-20 breast cancer cells that express high native levels of MCT1, but do not express MCT4 and are known to those... | US Patent US10202350 (2019) BindingDB Entry DOI: 10.7270/Q20K2BPB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Monocarboxylate transporter 1 (Homo sapiens (Human)) | BDBM345265 (2-[[1-[(2-Chlorophenyl)methyl]-5-(m- tolyl)pyrazo...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | n/a | n/a | 2.90E+4 | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Citation and Details | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Monocarboxylate transporter 4 (Homo sapiens (Human)) | BDBM345265 (2-[[1-[(2-Chlorophenyl)methyl]-5-(m- tolyl)pyrazo...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 25 | n/a | n/a | n/a | n/a | n/a | n/a |
Vettore, LLC US Patent | Assay Description NCI-H358 lung adenocarcinoma cells may be used to measure MCT4 activity in cells with high native levels of MCT4 and low levels of MCT1 and are known... | US Patent US10214492 (2019) BindingDB Entry DOI: 10.7270/Q2Q81GC0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Monocarboxylate transporter 1 (Homo sapiens (Human)) | BDBM345265 (2-[[1-[(2-Chlorophenyl)methyl]-5-(m- tolyl)pyrazo...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 2.90E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Vettore, LLC US Patent | Assay Description MCT1 activity may be measured using BT-20 breast cancer cells that express high native levels of MCT1, but do not express MCT4 and are known to those... | US Patent US10214492 (2019) BindingDB Entry DOI: 10.7270/Q2Q81GC0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Monocarboxylate transporter 4 (Homo sapiens (Human)) | BDBM345265 (2-[[1-[(2-Chlorophenyl)methyl]-5-(m- tolyl)pyrazo...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | n/a | n/a | 25 | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Citation and Details | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Monocarboxylate transporter 4 (Homo sapiens (Human)) | BDBM345265 (2-[[1-[(2-Chlorophenyl)methyl]-5-(m- tolyl)pyrazo...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 45 | n/a | n/a | n/a | n/a | n/a | n/a |
Vettore, LLC US Patent | Assay Description MCT4 may be stably expressed in MDA-MB-453 breast cancer cells that do not express native MCT1 or MCT4. MCT4 activity may be assessed by monitoring t... | US Patent US10214492 (2019) BindingDB Entry DOI: 10.7270/Q2Q81GC0 | |||||||||||
More data for this Ligand-Target Pair |