BDBM346019 US10202370, Example 020::[6-Methyl-2-(3- morpholin-4- ylmethyl-5- trifluoromethyl- phenyl)-3H- benzoimidazol-5-yl]- (4-pyridin-3-yl- thiazol-2-yl)-amine

SMILES: Cc1cc2nc([nH]c2cc1Nc1nc(cs1)-c1cccnc1)-c1cc(CN2CCOCC2)cc(c1)C(F)(F)F

InChI Key: InChIKey=UHFXBTHPZIOOCI-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 346019   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human))	BDBM346019 (US10202370, Example 020 | [6-Methyl-2-(3- morpholi...) Show SMILES Cc1cc2nc([nH]c2cc1Nc1nc(cs1)-c1cccnc1)-c1cc(CN2CCOCC2)cc(c1)C(F)(F)F Show InChI InChI=1S/C28H25F3N6OS/c1-17-9-23-24(13-22(17)35-27-36-25(16-39-27)19-3-2-4-32-14-19)34-26(33-23)20-10-18(11-21(12-20)28(29,30)31)15-37-5-7-38-8-6-37/h2-4,9-14,16H,5-8,15H2,1H3,(H,33,34)(H,35,36)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	<1.00E+3	n/a	n/a	n/a	n/a
AB SCIENCE US Patent					Assay Description Colorimetric cell proliferation and viability assay (reagent CellTiter-Blue purchased from Promega cat N°G8081) was performed on BaF3 Kit WT cell lin...				US Patent US10202370 (2019) BindingDB Entry DOI: 10.7270/Q2Q52RRK
					More data for this Ligand-Target Pair