BDBM346029 (6-Methyl-2-m-tolyl- 3H-benzoimidazol-5- yl)-(4-pyridin-4-yl- thiazol-2-yl)-amine::US10202370, Example 034

SMILES: Cc1cccc(c1)-c1nc2cc(C)c(Nc3nc(cs3)-c3ccncc3)cc2[nH]1

InChI Key: InChIKey=DYVDVXVZVQDJDE-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 346029   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human))	BDBM346029 ((6-Methyl-2-m-tolyl- 3H-benzoimidazol-5- yl)-(4-py...) Show SMILES Cc1cccc(c1)-c1nc2cc(C)c(Nc3nc(cs3)-c3ccncc3)cc2[nH]1 Show InChI InChI=1S/C23H19N5S/c1-14-4-3-5-17(10-14)22-25-19-11-15(2)18(12-20(19)26-22)27-23-28-21(13-29-23)16-6-8-24-9-7-16/h3-13H,1-2H3,(H,25,26)(H,27,28)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	<1.00E+3	n/a	n/a	n/a	n/a
AB SCIENCE US Patent					Assay Description Colorimetric cell proliferation and viability assay (reagent CellTiter-Blue purchased from Promega cat N°G8081) was performed on BaF3 Kit WT cell lin...				US Patent US10202370 (2019) BindingDB Entry DOI: 10.7270/Q2Q52RRK
					More data for this Ligand-Target Pair