BDBM346063 US10202370, Example 101::[1-Isopropyl-6- methyl-2-(3- trifluoromethyl- phenyl)-1H- benzoimidazol-5-yl]- (4-pyridin-4-yl- thiazol-2-yl)-amine
SMILES: CC(C)n1c(nc2cc(Nc3nc(cs3)-c3ccncc3)c(C)cc12)-c1cccc(c1)C(F)(F)F
InChI Key: InChIKey=UENKPGFLSLACJF-UHFFFAOYSA-N
Data: 1 EC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human)) | BDBM346063 (US10202370, Example 101 | [1-Isopropyl-6- methyl-2...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | <1.00E+3 | n/a | n/a | n/a | n/a |
AB SCIENCE US Patent | Assay Description Colorimetric cell proliferation and viability assay (reagent CellTiter-Blue purchased from Promega cat N°G8081) was performed on BaF3 Kit WT cell lin... | US Patent US10202370 (2019) BindingDB Entry DOI: 10.7270/Q2Q52RRK | |||||||||||
More data for this Ligand-Target Pair |